Microscopic colitis: A retrospective study of clinical presentation in 53 patients

被引：37

作者：

Barta, Zsolt ^{[1
]}

Mekkel, Gabriella ^{[1
]}

Csipo, Istvan ^{[1
]}

Toth, Laszlo ^{[2
]}

Szakall, Szabolcs ^{[2
]}

Szabo, Gabor G. ^{[1
]}

Bako, Gyula ^{[1
]}

Szegedi, Gyula ^{[1
]}

Zeher, Margit ^{[1
]}

机构：

[1] Univ Debrecen, Med & Hlth Sci Ctr, Fac Med, Dept Med 3, H-4012 Debrecen, Hungary

[2] Univ Debrecen, Med & Hlth Sci Ctr, Dept Pathol, Fac Med, H-4012 Debrecen, Hungary

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2005年 / 11卷 / 09期

关键词：

Microscopic colitis; Constipation; Autoimmune;

D O I：

10.3748/wjg.v11.i9.1351

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

AIM: To evaluate the relationship between symptoms and microscopic colitis (MC) subtypes: to test whether collagenous colitis (CC) and/or lymphocytic colitis (LC) might be related to both constipation and diarrhea. METHODS: A cohort of patients with independently confirmed typical histopathological changes was investigated. Fifty-three patients with histologically proved MC (46 with CC, 7 with LC) were included. The existence of diarrhea or constipation and the co-existence of autoimmune diseases were also investigated and all data were retrospectively analyzed. RESULTS: Twenty-three (43.39%) of MC patients had chronic constipation (20 in CC, 3 in LC patients). Twenty-four (45.28%) of MC patients had autoimmune disease and the diagnosis of autoimmune disease was always prior to MC. Sjogren's syndrome was associated only with the constipation subgroup. CONCLUSION: The Janus face of MC resembles the subgroups of irritable bowel syndrome. The co-existence of autoimmune diseases and MC is confirmed in both the constipation and diarrhea subgroups. (C) 2005 The WJG Press and Elsevier Inc. All rights reserved.

引用

页码：1351 / 1355

页数：5

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