Simultaneous determination of cysteamine and folic acid in pharmaceutical and biological samples using modified multiwall carbon nanotube paste electrode

被引：59
作者：
Taherkhani, Ali [2 ]
Karimi-Maleh, Hassan [1 ]
Ensafi, Ali A. [1 ]
Beitollahi, Hadi [3 ]
Hosseini, Ahmad [4 ]
Khalilzadeh, Mohammad A. [4 ]
Bagheri, Hassan [5 ]
机构：
[1] Islamic Azad Univ, Majlesi Branch, Dept Chem, Esfahan, Iran
[2] Islamic Azad Univ, Takestan Branch, Dept Phys, Takestan, Iran
[3] Int Ctr Sci High Technol & Environm Sci, Res Inst Environm Sci, Dept Environm, Kerman, Iran
[4] Islamic Azad Univ, Qaemshahr Branch, Dept Chem, Qaemshahr, Iran
[5] Islamic Azad Univ, Takestan Branch, Dept Chem, Takestan, Iran
来源：
CHINESE CHEMICAL LETTERS | 2012年 / 23卷 / 02期
关键词：
Cysteamine; Folic acid; Carbon nanotube paste electrode; Voltammetry; SENSOR;
D O I：
10.1016/j.cclet.2011.10.023
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A carbon paste electrode (CPE) chemically modified with multiwall carbon nanotubes and ferrocene (FC) was used as a selective electrochemical sensor for the simultaneous determination of trace amounts of cysteamine (CA) and folic acid (FA). This modified electrode showed very efficient electrocatalytic activity for the anodic oxidation of CA. The peak current of differential pulse voltammograms of CA and FA increased linearly with their concentration in the ranges of 0.7-200 mu mol/L CA and 5.0-700 mu mol/L FA. The detection limits for CA and FA were 0.3 mu mol/L and 2.0 mu mol/L, respectively. The diffusion coefficient (D) and transfer coefficient (alpha) of CA were also determined. These conditions are sufficient to allow determination of CA and FA both individually and simultaneously. (C) 2011 Hassan Karimi-Maleh. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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页码：237 / 240
页数：4
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