Gold-catalyzed synthesis of 2,5-dihydrofurans in ionic liquids

被引：52
作者：
Aksin, Oezge [1 ]
Krause, Norbert [1 ]
机构：
[1] Dortmund Univ Technol, D-44227 Dortmund, Germany
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2008年 / 350卷 / 7-8期
关键词：
allenes; chirality transfer; cycloisomerization; gold catalysis; ionic liquids;
D O I：
10.1002/adsc.200800050
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Nine alpha-hydroxyallenes 1/3 were cyclized to the corresponding 2,5-dihydrofurans 2/4 with complete axis-to-center chirality transfer in the presence of 1 mol% of AuBr3 using [BMIM] [PF6] as solvent at room temperature. The gold catalyst/ionic liquid system is air-stable and recyclable. The leaching of the gold catalyst upon extraction of the product is extremely low (0.03% after five runs).
引用
收藏
页码：1106 / 1112
页数：7
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