Comparison of point shear wave elastography and transient elastography in the evaluation of patients with NAFLD

被引:24
作者
Argalia, Giulio [1 ]
Ventura, Claudio [1 ]
Tosi, Niccolo [1 ]
Campioni, Daniele [1 ]
Tagliati, Corrado [1 ]
Tufillaro, Marianna [1 ]
Cucco, Monica [2 ]
Baroni, Gianluca Svegliati [2 ]
Giovagnoni, Andrea [1 ]
机构
[1] Univ Politecn Marche, Univ Hosp, Dept Radiol Sci, Osped Riuniti Ancona, Via Tronto 10, I-60126 Ancona, Italy
[2] Univ Politecn Marche, Univ Hosp, Obes Ctr, Liver Insult & Transplant Unit,Osped Riuniti Anco, Via Tronto 10, I-60126 Ancona, Italy
来源
RADIOLOGIA MEDICA | 2022年 / 127卷 / 05期
关键词
Point shear wave elastography; Transient elastography; Liver stiffness; Non-alcoholic fatty liver disease; Liver biopsy; FATTY LIVER-DISEASE; BIOPSY;
D O I
10.1007/s11547-022-01475-8
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose To compare point shear wave elastography (pSWE, ElastPQ (R)) and transient elastography (TE) with Liver Biopsy in order to evaluate fibrosis stage in non-alcoholic fatty liver disease (NAFLD). Methods Our prospective study from September 2017 to October 2020 included 50 consecutively enrolled patients with NAFLD (52.2 +/- 13.0 years, 32 male). All patients underwent clinical evaluation, B-mode ultrasound, pSWE, TE and liver biopsy in a single evaluation. The clinical, laboratory and liver biopsy data were compared with liver stiffness (LS) measurement obtained with pSWE and TE. TE and pSWE diagnostic accuracy for the diagnosis of the different fibrosis stages were evaluated using the area under receiver operating characteristic curve (AUROC). Results Only fibrosis stage was independently associated with TE and pSWE. The median liver stiffness measurement for fibrosis stages F0, F1, F2, F3, and F4 using TE was 4.8 (4.7-6.1) kPa, 5.5 (4.4-7.3) kPa, 7.7 (6.1-9.1) kPa, 9.9 (8.8-13.8) kPa, and 20.2 kPa, respectively. The corresponding median liver stiffness measurement using pSWE was 4.2 (4.0-4.8) kPa, 4.7 (4.2-5.8) kPa, 5.1 (4.1-6.9) kPa, 8.5 (5.2-13.3), and 15.1 kPa, respectively. The AUROC of TE for diagnosis of fibrosis stage F1, >= F2, >= F3, and F4 were 0.795, 0.867, 0.927, and 0.990, respectively. The corresponding AUROC of pSWE was 0.717, 0.733, 0.908, and 1.000, respectively. No association was observed with other histological parameters. Conclusion TE was significantly better than pSWE for the diagnosis of fibrosis stage >= F2. No statistically significant differences were found between TE and pSWE AUROC of fibrosis stage >= F1, >= F3, and F4.
引用
收藏
页码:571 / 576
页数:6
相关论文
共 23 条
[1]   Global epidemiology of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: What we need in the future [J].
Araujo, Ana Ruth ;
Rosso, Natalia ;
Bedogni, Giorgio ;
Tiribelli, Claudio ;
Bellentani, Stefano .
LIVER INTERNATIONAL, 2018, 38 :47-51
[2]   Shear wave elastography and transient elastography in HCV patients after direct-acting antivirals [J].
Argalia, Giulio ;
Tarantino, Giuseppe ;
Ventura, Claudio ;
Campioni, Daniele ;
Tagliati, Corrado ;
Guardati, Paola ;
Kostandini, Alba ;
Marzioni, Marco ;
Giuseppetti, Gian Marco ;
Giovagnoni, Andrea .
RADIOLOGIA MEDICA, 2021, 126 (06) :894-899
[3]   Liver stiffness measurement using acoustic radiation force impulse elastography in overweight and obese patients [J].
Attia, D. ;
Bantel, H. ;
Lenzen, H. ;
Manns, M. P. ;
Gebel, M. J. ;
Potthoff, A. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2016, 44 (04) :366-379
[4]   Prevalence of and risk factors for nonalcoholic fatty liver disease: The Dionysos Nutrition and Liver Study [J].
Bedogni, G ;
Miglioli, L ;
Masutti, F ;
Tiribelli, C ;
Marchesini, G ;
Bellentani, S .
HEPATOLOGY, 2005, 42 (01) :44-52
[5]   Determination of reliability criteria for liver stiffness evaluation by transient elastography [J].
Boursier, Jerome ;
Zarski, Jean-Pierre ;
de Ledinghen, Victor ;
Rousselet, Marie-Christine ;
Sturm, Nathalie ;
Lebail, Brigitte ;
Fouchard-Hubert, Isabelle ;
Gallois, Yves ;
Oberti, Frederic ;
Bertrais, Sandrine ;
Cales, Paul .
HEPATOLOGY, 2013, 57 (03) :1182-1191
[6]   Liver Stiffness in Nonalcoholic Fatty Liver Disease: A Comparison of Supersonic Shear Imaging, FibroScan, and ARFI With Liver Biopsy [J].
Cassinotto, Christophe ;
Boursier, Jerome ;
de Ledinghen, Victor ;
Lebigot, Jerome ;
Lapuyade, Bruno ;
Cales, Paul ;
Hiriart, Jean-Baptiste ;
Michalak, Sophie ;
Le Bail, Brigitte ;
Cartier, Victoire ;
Mouries, Amaury ;
Oberti, Frederic ;
Fouchard-Hubert, Isabelle ;
Vergniol, Julien ;
Aube, Christophe .
HEPATOLOGY, 2016, 63 (06) :1817-1827
[7]   EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography. Part 2: Clinical Applications [J].
Cosgrove, D. ;
Piscaglia, F. ;
Bamber, J. ;
Bojunga, J. ;
Correas, J. -M. ;
Gilja, O. H. ;
Klauser, A. S. ;
Sporea, I. ;
Calliada, F. ;
Cantisani, V. ;
D'Onofrio, M. ;
Drakonaki, E. E. ;
Fink, M. ;
Friedrich-Rust, M. ;
Fromageau, J. ;
Havre, R. F. ;
Jenssen, C. ;
Ohlinger, R. ;
Saftoiu, A. ;
Schaefer, F. ;
Dietrich, C. F. .
ULTRASCHALL IN DER MEDIZIN, 2013, 34 (03) :238-253
[8]  
Dietrich CF, 2017, ULTRASCHALL MED, V38, pE52, DOI [10.1055/a-0641-0076, 10.1055/s-0043-103952]
[9]  
EASL, 2016, OBESITY FACTS, V9, P65, DOI [10.1007/s00125-016-3902-y, 10.1159/000443344, 10.1016/j.jhep.2015.11.004]
[10]   Adherence to quality criteria improves concordance between transient elastography and ElastPQ for liver stiffness assessment-A multicenter retrospective study [J].
Ferraioli, Giovanna ;
De Silvestri, Annalisa ;
Reiberger, Thomas ;
Taylor-Robinson, Simon D. ;
de Knegt, Robert J. ;
Maiocchi, Laura ;
Mare, Ruxandra ;
Bucsics, Theresa ;
Atzori, Sebastiana ;
Tinelli, Carmine ;
Sporea, Ioan .
DIGESTIVE AND LIVER DISEASE, 2018, 50 (10) :1056-1061