Alternate measure of information useful for DNA sequences

被引:18
作者
Bose, Ranjan [1 ]
Chouhan, Sonali [2 ]
机构
[1] IIT Delhi, Dept Elect Engn, New Delhi, India
[2] IIT Guwahati, Dept Elect & Elect Engn, Gauhati, India
来源
PHYSICAL REVIEW E | 2011年 / 83卷 / 05期
关键词
NONCODING DNA; ENTROPY; GENE;
D O I
10.1103/PhysRevE.83.051918
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We propose an alternate measure of information, called superinformation, which has been found to be very effective for analyzing the coding and noncoding regions of the DNA. This superinformation is actually a measure of the "randomness of randomness." It has been found to be highly accurate in classifying coding and noncoding regions of human DNA. In the proposed method, no prior training is required. This technique exhibits higher accuracy than previously reported techniques in distinguishing between the coding and the noncoding portions of the DNA. Superinformation can also be used to analyze the untranslated regions in various genes.
引用
收藏
页数:6
相关论文
共 27 条
[1]   Adaptive evolution of non-coding DNA in Drosophila [J].
Andolfatto, P .
NATURE, 2005, 437 (7062) :1149-1152
[2]  
[Anonymous], 1959, Theory of Probablity and Its Applications
[3]   Finding borders between coding and noncoding DNA regions by an entropic segmentation method [J].
Bernaola-Galván, P ;
Grosse, I ;
Carpena, P ;
Oliver, JL ;
Román-Roldán, R ;
Stanley, HE .
PHYSICAL REVIEW LETTERS, 2000, 85 (06) :1342-1345
[4]  
Bose R., 2002, INFORM THEORY CODING
[5]  
FARACH M, 1995, PROCEEDINGS OF THE SIXTH ANNUAL ACM-SIAM SYMPOSIUM ON DISCRETE ALGORITHMS, P48
[6]   ASSESSMENT OF PROTEIN CODING MEASURES [J].
FICKETT, JW ;
TUNG, CS .
NUCLEIC ACIDS RESEARCH, 1992, 20 (24) :6441-6450
[7]  
GRANTHAM R, 1981, NUCLEIC ACIDS RES, V9, pR43
[8]   FINITE-SAMPLE CORRECTIONS TO ENTROPY AND DIMENSION ESTIMATES [J].
GRASSBERGER, P .
PHYSICS LETTERS A, 1988, 128 (6-7) :369-373
[9]   Species independence of mutual information in coding and noncoding DNA [J].
Grosse, I ;
Herzel, H ;
Buldyrev, SV ;
Stanley, HE .
PHYSICAL REVIEW E, 2000, 61 (05) :5624-5629
[10]  
Harris B., 1975, Topics. Inf. Theory, V16, P323