EVALUATION OF THE INTRAEPITHELIAL PAPILLARY CAPILLARY LOOPS IN BENIGN AND MALIGNANT ORAL LESIONS BY IN VIVO VIRTUAL CHROMOENDOSCOPIC MAGNIFICATION: A PRELIMINARY STUDY

被引:0
作者
Contaldo, M. [1 ]
Lucchese, A. [1 ]
Gentile, E. [1 ]
Zulli, C. [2 ]
Petruzzi, M. [3 ]
Lauritano, D. [4 ]
Amato, M. R. [2 ]
Esposito, P. [2 ]
Riegler, G. [2 ]
Serpico, R. [1 ]
机构
[1] Univ Campania Luigi Vanvitelli, Multidisciplinary Dept Med Surg & Odontostomatol, Via L De Crecchio 6, I-80138 Naples, Italy
[2] Univ Campania Luigi Vanvitelli, Dept Clin & Expt Med Gastroenterol, Naples, Italy
[3] Univ Bari Aldo Moro, Dipartimento Interdisciplinare Med, Sez Malattie Odontostomatol, Policlin Bari, Bari, Italy
[4] Univ Milano Bicocca, Dept Med & Surg, Monza, Italy
关键词
virtual chromoendoscopic magnification; narrow band imaging; oral cancer; oral pathology; non-invasive imaging; SQUAMOUS-CELL CARCINOMA; ENDOTHELIAL GROWTH-FACTOR; LICHEN-PLANUS; ANGIOGENIC ACTIVITY; OPTICAL BIOPSY; NECK-CANCER; FEATURES; MUCOSA; PROGRESSION; EXPRESSION;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This preliminary study aims to establish the Virtual Chromoendoscopic Magnification (VCM) feasibility to visualize and distinguish the Intraepithelial Papillary Capillary Loops (IPCL) patterns of benign oral pathologies from malignant ones. Thirty-one consecutive subjects affected by oral lesions/pathologies underwent white light examination and VCM imaging by the Narrow Band Imaging System (Olympus Medical Systems Corp., Tokyo, Japan). A class system of four IPCL types corresponding to progressive vessel disarray was adopted. IPCL type IV were considered criterion of "malignancy". A histopathological exam completed the diagnosis: sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated. IPCL patterns of benign oral entities ranged from types I to III. IPCL type IV was associated with malignancy in 4 out of 6 cases. Sensitivity, specificity, PPV, and NPV were 100%, 93%, 67% and 100%, respectively. This study preliminarily describes IPCL patterns of different oral mucosal diseases and confirms the association between IPCL IV and oral cancer.
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页码:11 / 22
页数:12
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