Fluorescent labeling of human mesenchymal stem cells by thiophene fluorophores conjugated to a lipophilic carrier

被引：21

作者：

Duca, Maria ^{[1
]}

Dozza, Barbara ^{[2
]}

Lucarelli, Enrico ^{[2
]}

Santi, Spartaco ^{[3
]}

Di Giorgio, Audrey ^{[1
]}

Barbarella, Giovanna ^{[4
,5
]}

机构：

[1] Univ Nice Sophia Antipolis, Inst Chim Nice, CNRS, LCMBA,UMR6001, F-06100 Nice, France

[2] Rizzoli Orthoped Inst, I-40136 Bologna, Italy

[3] CNR, Ist Genet Mol, I-40126 Bologna, Italy

[4] ISOF CNR, I-40129 Bologna, Italy

[5] Mediteknology Srl, CNR, I-40129 Bologna, Italy

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 42期

关键词：

REGENERATIVE MEDICINE; MITOCHONDRIA; DELIVERY; CATIONS; BONE; DNA;

D O I：

10.1039/c0cc01918f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fluorescent labeling of human mesenchymal stem cells (hMSCs) is essential for their study in vitro and in vivo. Here, we report a new chemical biodelivery method for labeling hMSCs using a series of very efficient and highly versatile thiophene-based fluorescent dyes. Such conjugates contribute to a stable and viable labeling of hMSCs and constitute a promising strategy for in vivo applications.

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收藏

页码：7948 / 7950

页数：3

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