Utility of (p-sulfonamidophenyl)azomalononitrile, and ethyl acetoacetate in synthesis of fused azole and azines derivatives II

被引：10

作者：

Hassanien, AA ^{[1
]}

Amr, AE

Ghozlan, SAS

机构：

[1] Suez Canal Univ, Fac Educ, Dept Chem, Al Arish, Egypt

[2] Natl Res Ctr, Dept Appl Organ Chem, Cairo, Egypt

[3] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2000年 / 47卷 / 06期

关键词：

(p-sulfonamidophenyl)azomalononitrile; ellylacetoacetate; 2-cyanoacetohydrazides; triazolol[1,5-a]pyrimidines and azines;

D O I：

10.1002/jccs.200000176

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[(p-Sulfonamidophenyl)azo]malononitrile (1a,b) reacted with N-cyclohexanemethylidene-2-cyano-acetohydrazide, N'-arylmethylidene-2-cyanoacetohydrazide (3a-c), S-methylthiourea and hydrazine hydrate to afford [1,2,4]triazolo-[1,5-alpha ]pyridinone derivatives (2a,b) & (4a-c), substituted pyrimidines 5a,b and 6a,b. The corresponding pyridazinones 7a,b were synthesized from the reaction of 1c,d with ethyl cyanoacetate. Compound 7a,b reacted with elemental sulfur to yield 8a,b. Compound 6a underwent cycloaddition with alpha -cinnamonitrile 9a-e to yield 11a-c, 14 and 15. Also, compound 6a reacted with beta -ketoester and 1,3-diketones to give 16, 17 and 18.

引用

页码：1273 / 1278

页数：6

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