All for One, and One for All

被引：1

作者：

Kim, Eiru ^{[1
]}

Hart, Traver ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA

来源：

CELL SYSTEMS | 2017年 / 5卷 / 04期

关键词：

PROTEOGENOMIC CHARACTERIZATION; CANCER;

D O I：

10.1016/j.cels.2017.10.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hemizygous deletion of a gene in tumor cells frequently causes reduced expression of its encoded mRNA and protein, as well as reduced protein-but not mRNA-expression of other members in the same protein complex.

引用

页码：314 / 316

页数：4

共 10 条

[1] Connecting Genomic Alterations to Cancer Biology with Proteomics: The NCI Clinical Proteomic Tumor Analysis Consortium [J].

Ellis, Matthew J. ;

Gillette, Michael ;

Carr, Steven A. ;

Paulovich, Amanda G. ;

Smith, Richard D. ;

Rodland, Karin K. ;

Townsend, R. Reid ;

Kinsinger, Christopher ;

Mesri, Mehdi ;

Rodriguez, Henry ;

Liebler, Daniel C. .

CANCER DISCOVERY, 2013, 3 (10) :1108-1112

[2] Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer [J].

Goncalves, Emanuel ;

Fragoulis, Athanassios ;

Garcia-Alonso, Luz ;

Cramer, Thorsten ;

Saez-Rodriguez, Julio ;

Beltrao, Pedro .

CELL SYSTEMS, 2017, 5 (04) :386-+

[3] Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens [J].

Hart, Traver ;

Tong, Amy Hin Yan ;

Chan, Katie ;

Van Leeuwen, Jolanda ;

Seetharaman, Ashwin ;

Aregger, Michael ;

Chandrashekhar, Megha ;

Hustedt, Nicole ;

Seth, Sahil ;

Noonan, Avery ;

Habsid, Andrea ;

Sizova, Olga ;

Nedyalkova, Lyudmila ;

Climie, Ryan ;

Tworzyanski, Leanne ;

Lawson, Keith ;

Sartori, Maria Augusta ;

Alibeh, Sabriyeh ;

Tieu, David ;

Masud, Sanna ;

Mero, Patricia ;

Weiss, Alexander ;

Brown, Kevin R. ;

Usaj, Matej ;

Billmann, Maximilian ;

Rahman, Mahfuzur ;

Constanzo, Michael ;

Myers, Chad L. ;

Andrews, Brenda J. ;

Boone, Charles ;

Durocher, Daniel ;

Moffat, Jason .

G3-GENES GENOMES GENETICS, 2017, 7 (08) :2719-2727

[4] A Landscape of Pharmacogenomic Interactions in Cancer [J].

Iorio, Francesco ;

Knijnenburg, Theo A. ;

Vis, Daniel J. ;

Bignell, Graham R. ;

Menden, Michael P. ;

Schubert, Michael ;

Aben, Nanne ;

Goncalves, Emanuel ;

Barthorpe, Syd ;

Lightfoot, Howard ;

Cokelaer, Thomas ;

Greninger, Patricia ;

van Dyk, Ewald ;

Chang, Han ;

de Silva, Heshani ;

Heyn, Holger ;

Deng, Xianming ;

Egan, Regina K. ;

Liu, Qingsong ;

Mironenko, Tatiana ;

Mitropoulos, Xeni ;

Richardson, Laura ;

Wang, Jinhua ;

Zhang, Tinghu ;

Moran, Sebastian ;

Sayols, Sergi ;

Soleimani, Maryam ;

Tamborero, David ;

Lopez-Bigas, Nuria ;

Ross-Macdonald, Petra ;

Esteller, Manel ;

Gray, Nathanael S. ;

Haber, Daniel A. ;

Stratton, Michael R. ;

Benes, Cyril H. ;

Wessels, Lodewyk F. A. ;

Saez-Rodriguez, Julio ;

McDermott, Ultan ;

Garnett, Mathew J. .

CELL, 2016, 166 (03) :740-754

[5] Proteogenomics connects somatic mutations to signalling in breast cancer [J].

Mertins, Philipp ;

Mani, D. R. ;

Ruggles, Kelly V. ;

Gillette, Michael A. ;

Clauser, Karl R. ;

Wang, Pei ;

Wang, Xianlong ;

Qiao, Jana W. ;

Cao, Song ;

Petralia, Francesca ;

Kawaler, Emily ;

Mundt, Filip ;

Krug, Karsten ;

Tu, Zhidong ;

Lei, Jonathan T. ;

Gatza, Michael L. ;

Wilkerson, Matthew ;

Perou, Charles M. ;

Yellapantula, Venkata ;

Huang, Kuan-lin ;

Lin, Chenwei ;

McLellan, Michael D. ;

Yan, Ping ;

Davies, Sherri R. ;

Townsend, R. Reid ;

Skates, Steven J. ;

Wang, Jing ;

Zhang, Bing ;

Kinsinger, Christopher R. ;

Mesri, Mehdi ;

Rodriguez, Henry ;

Ding, Li ;

Paulovich, Amanda G. ;

Fenyo, David ;

Ellis, Matthew J. ;

Carr, Steven A. .

NATURE, 2016, 534 (7605) :55-+

[6] Cancer Vulnerabilities Unveiled by Genomic Loss [J].

Nijhawan, Deepak ;

Zack, Travis I. ;

Ren, Yin ;

Strickland, Matthew R. ;

Lamothe, Rebecca ;

Schumacher, Steven E. ;

Tsherniak, Aviad ;

Besche, Henrike C. ;

Rosenbluh, Joseph ;

Shehata, Shyemaa ;

Cowley, Glenn S. ;

Weir, Barbara A. ;

Goldberg, Alfred L. ;

Mesirov, Jill P. ;

Root, David E. ;

Bhatia, Sangeeta N. ;

Beroukhim, Rameen ;

Hahn, William C. .

CELL, 2012, 150 (04) :842-854

[7] A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events [J].

Ryan, Colm J. ;

Kennedy, Susan ;

Bajrami, Ilirjana ;

Matallanas, David ;

Lord, Christopher J. .

CELL SYSTEMS, 2017, 5 (04) :399-+

[8] Insights into the regulation of protein abundance from proteomic and transcriptomic analyses [J].

Vogel, Christine ;

Marcotte, Edward M. .

NATURE REVIEWS GENETICS, 2012, 13 (04) :227-232

[9] Proteogenomic characterization of human colon and rectal cancer [J].

Zhang, Bing ;

Wang, Jing ;

Wang, Xiaojing ;

Zhu, Jing ;

Liu, Qi ;

Shi, Zhiao ;

Chambers, Matthew C. ;

Zimmerman, Lisa J. ;

Shaddox, Kent F. ;

Kim, Sangtae ;

Davies, Sherri R. ;

Wang, Sean ;

Wang, Pei ;

Kinsinger, Christopher R. ;

Rivers, Robert C. ;

Rodriguez, Henry ;

Townsend, R. Reid ;

Ellis, Matthew J. C. ;

Carr, Steven A. ;

Tabb, David L. ;

Coffey, Robert J. ;

Slebos, Robbert J. C. ;

Liebler, Daniel C. .

NATURE, 2014, 513 (7518) :382-+

[10] Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer [J].

Zhang, Hui ;

Liu, Tao ;

Zhang, Zhen ;

Payne, Samuel H. ;

Zhang, Bai ;

McDermott, Jason E. ;

Zhou, Jian-Ying ;

Petyuk, Vladislav A. ;

Chen, Li ;

Ray, Debjit ;

Sun, Shisheng ;

Yang, Feng ;

Chen, Lijun ;

Wang, Jing ;

Shah, Punit ;

Cha, Seong Won ;

Aiyetan, Paul ;

Woo, Sunghee ;

Tian, Yuan ;

Gritsenko, Marina A. ;

Clauss, Therese R. ;

Choi, Caitlin ;

Monroe, Matthew E. ;

Thomas, Stefani ;

Nie, Song ;

Wu, Chaochao ;

Moore, Ronald J. ;

Yu, Kun-Hsing ;

Tabb, David L. ;

Fenyo, David ;

Bafna, Vineet ;

Wang, Yue ;

Rodriguez, Henry ;

Boja, Emily S. ;

Hiltke, Tara ;

Rivers, Robert C. ;

Sokoll, Lori ;

Zhu, Heng ;

Shih, Ie-Ming ;

Cope, Leslie ;

Pandey, Akhilesh ;

Zhang, Bing ;

Snyder, Michael P. ;

Levine, Douglas A. ;

Smith, Richard D. ;

Chan, Daniel W. ;

Rodland, Karin D. .

CELL, 2016, 166 (03) :755-765

← 1 →