Matrix metalloproteinases: old dogs with new tricks

被引：227
作者：
Somerville, RPT [1 ]
Oblander, SA [1 ]
Apte, SS [1 ]
机构：
[1] Cleveland Clin Fdn, Dept Biomed Engn, Cleveland, OH 44195 USA
来源：
GENOME BIOLOGY | 2003年 / 4卷 / 06期
关键词：
D O I：
10.1186/gb-2003-4-6-216
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The matrix metalloproteinase family in humans comprises 23 enzymes, which are involved in many biological processes and diseases. It was previously thought that these enzymes acted only to degrade components of the extracellular matrix, but this view has changed with the discovery that non-extracellular-matrix molecules are also substrates.
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页数：11
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