Investigation of biphasic calcium phosphate/gelatin nanocomposite scaffolds as a bone tissue engineering

被引：47

作者：

Bakhtiari, Leila ^{[1
]}

Rezaie, Hamid Reza ^{[1
]}

Hosseinalipour, Seyed Mohamad ^{[1
]}

Shokrgozar, Mohamad Ali ^{[2
]}

机构：

[1] Iran Univ Sci & Technol, Mat Engn & Met Dept, Tehran 16844, Narmak, Iran

[2] Pasteur Inst Iran, Natl Cell Bank Iran, Tehran 13164, Iran

来源：

CERAMICS INTERNATIONAL | 2010年 / 36卷 / 08期

关键词：

Sintering; Nanocomposite; Porosity; Biomedical application; Scaffold; HYDROXYAPATITE;

D O I：

10.1016/j.ceramint.2010.07.012

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The porous scaffold of nanobiphasic calcium phosphate (n-BCP) and gelatin from bovine skin type B was prepared by freeze-drying method. The porogen which used was Naphthalene. EDC (N-(3-dimethyl aminopropyl)-N'-ethyl carbodiimide hydrochloride) for stabilization of gelatin by cross-linking method was used. The scaffold was characterized by SEM, XRD and FTIR. As a result, a biocompatible scaffold with good cell attachment, facility in formation in desired shapes and simplicity in production were prepared for bone tissue engineering. (C) 2010 Elsevier Ltd and Techna Group S.r.l. All rights reserved.

引用

页码：2421 / 2426

页数：6