Investigation of biphasic calcium phosphate/gelatin nanocomposite scaffolds as a bone tissue engineering

The porous scaffold of nanobiphasic calcium phosphate (n-BCP) and gelatin from bovine skin type B was prepared by freeze-drying method. The porogen which used was Naphthalene. EDC (N-(3-dimethyl aminopropyl)-N'-ethyl carbodiimide hydrochloride) for stabilization of gelatin by cross-linking method was used. The scaffold was characterized by SEM, XRD and FTIR. As a result, a biocompatible scaffold with good cell attachment, facility in formation in desired shapes and simplicity in production were prepared for bone tissue engineering. (C) 2010 Elsevier Ltd and Techna Group S.r.l. All rights reserved.