How "immunomodulatory" are IMIDs?

被引:11
作者
Mitsiades, Constantine S. [1 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02215 USA
关键词
MULTIPLE-MYELOMA; LENALIDOMIDE; THALIDOMIDE;
D O I
10.1182/blood-2010-11-317156
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1440 / 1441
页数:3
相关论文
共 10 条
[1]   Lenalidomide and thalidomide: An evolving paradigm for the management of multiple myeloma - Introduction [J].
Anderson, KC ;
Prince, HM .
SEMINARS IN HEMATOLOGY, 2005, 42 (04) :S1-S2
[2]  
Attal, 2010, J CLIN ONCOL, V28, P4402
[3]   Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma [J].
Davies, FE ;
Raje, N ;
Hideshima, T ;
Lentzsch, S ;
Young, G ;
Tai, YT ;
Lin, B ;
Podar, K ;
Gupta, D ;
Chauhan, D ;
Treon, SP ;
Richardson, PG ;
Schlossman, RL ;
Morgan, GJ ;
Muller, GW ;
Stirling, DI ;
Anderson, KC .
BLOOD, 2001, 98 (01) :210-216
[4]  
Gandhi AK, 2010, CURR CANCER DRUG TAR, V10, P155
[5]   The immunostimulatory effect of lenalidomide on NK-cell function is profoundly inhibited by concurrent dexamethasone therapy [J].
Hsu, Andy K. ;
Quach, Hang ;
Tai, Tsin ;
Prince, H. Miles ;
Harrison, Simon J. ;
Trapani, Joseph A. ;
Smyth, Mark J. ;
Neeson, Paul ;
Ritchie, David S. .
BLOOD, 2011, 117 (05) :1605-1613
[6]   Pomalidomide (CC4047) Plus Low-Dose Dexamethasone As Therapy for Relapsed Multiple Myeloma [J].
Lacy, Martha Q. ;
Hayman, Suzanne R. ;
Gertz, Morie A. ;
Dispenzieri, Angela ;
Buadi, Francis ;
Kumar, Shaji ;
Greipp, Philip R. ;
Lust, John A. ;
Russell, Stephen J. ;
Dingli, David ;
Kyle, Robert A. ;
Fonseca, Rafael ;
Bergsagel, P. Leif ;
Roy, Vivek ;
Mikhael, Joseph R. ;
Stewart, A. Keith ;
Laumann, Kristina ;
Allred, Jacob B. ;
Mandrekar, Sumithra J. ;
Rajkumar, S. Vincent .
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (30) :5008-5014
[7]   Phase III intergroup study of lenalfdomide versus placebo maintenance therapy following single autologous stem cell transplant (ASCT) for multiple myeloma (MM): CALGB 100104 [J].
McCarthy, P. L. ;
Owzar, K. ;
Anderson, K. C. ;
Hofmeister, C. C. ;
Hassoun, H. ;
Hurd, D. D. ;
Stadtmauer, E. A. ;
Giralt, S. ;
Hars, V. ;
Linker, C. A. .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15)
[8]   Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial [J].
Rajkumar, S. Vincent ;
Jacobus, Susanna ;
Callander, Natalie S. ;
Fonseca, Rafael ;
Vesole, David H. ;
Williams, Michael E. ;
Abonour, Rafat ;
Siegel, David S. ;
Katz, Michael ;
Greipp, Philip R. .
LANCET ONCOLOGY, 2010, 11 (01) :29-37
[9]   Safety and efficacy of single-agent lenalidomide in patients with relapsed and refractory multiple myeloma [J].
Richardson, Paul ;
Jagannath, Sundar ;
Hussein, Mohamad ;
Berenson, James ;
Singhal, Seema ;
Irwin, David ;
Williams, Stephanie F. ;
Bensinger, William ;
Badros, Ashraf Z. ;
Vescio, Robert ;
Kenvin, Laurie ;
Yu, Zhinuan ;
Olesnyckyj, Marta ;
Zeldis, Jerome ;
Knight, Robert ;
Anderson, Kenneth C. .
BLOOD, 2009, 114 (04) :772-778
[10]   Multicenter, Phase I, Dose-Escalation Trial of Lenalidomide Plus Bortezomib for Relapsed and Relapsed/Refractory Multiple Myeloma [J].
Richardson, Paul G. ;
Weller, Edie ;
Jagannath, Sundar ;
Avigan, David E. ;
Alsina, Melissa ;
Schlossman, Robert L. ;
Mazumder, Amitabha ;
Munshi, Nikhil C. ;
Ghobrial, Irene M. ;
Doss, Deborah ;
Warren, Diane L. ;
Lunde, Laura E. ;
McKenney, Mary ;
Delaney, Carol ;
Mitsiades, Constantine S. ;
Hideshima, Teru ;
Dalton, William ;
Knight, Robert ;
Esseltine, Dixie-Lee ;
Anderson, Kenneth C. .
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (34) :5713-5719