Medical Applications of Solid Nitrosyl Complexes

被引：3
作者：
Allan, Phoebe K. [1 ]
Morris, Russell E. [2 ]
机构：
[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England
[2] Univ St Andrews, EaStCHEM Sch Chem, St Andrews KY16 9ST, Fife, Scotland
来源：
NITROSYL COMPLEXES IN INORGANIC CHEMISTRY, BIOCHEMISTRY AND MEDICINE II | 2014年 / 154卷
关键词：
Gas adsorption; Medical applications; Metal-organic frameworks; Nitric oxide; METAL-ORGANIC FRAMEWORKS; CARBON-MONOXIDE INHALATION; NITRIC-OXIDE; HYDROGEN-SULFIDE; SORPTION COMPLEXES; CRYSTAL-STRUCTURES; RUTHENIUM NITROSYLS; SELECTIVE SORPTION; MANGANESE NITROSYL; SULFUR-DIOXIDE;
D O I：
10.1007/430_2013_105
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Solid nitrosyl compounds are under investigation as ways of delivering nitric oxide for medical applications. This contribution discusses the role of nitric oxide in biology and the need for solids that can be used to store and deliver the gas in biologically relevant amounts. The types of solid that make suitable gas storage media are discussed, as is the relationship between nitric oxide storage and other areas of gas storage research. The particular materials that show most promise for nitric oxide delivery are discussed in detail, including their preliminary medical applications on humans. Finally, a forward look is described as to how current nitric oxide technology is informing other potential gas delivery applications in medicine.
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收藏
页码：225 / 256
页数：32
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