Water near bioinert self-assembled monolayers

被引:20
|
作者
Chang, Ryongsok [1 ]
Asatyas, Syifa [1 ]
Lkhamsuren, Ganchimeg [1 ]
Hirohara, Makoto [1 ]
Mondarte, Evan Angelo Quimada [1 ]
Suthiwanich, Kasinan [1 ]
Sekine, Taito [1 ]
Hayashi, Tomohiro [1 ,2 ,3 ]
机构
[1] Tokyo Inst Technol, Dept Mat Sci & Engn, Sch Mat & Chem Technol, Yokohama, Kanagawa, Japan
[2] RIKEN, Surface & Interface Sci, Wako, Saitama, Japan
[3] JST PRESTO, Kawaguchi, Saitama, Japan
关键词
LATERAL PACKING DENSITY; PROTEIN ADSORPTION; MOLECULAR SIMULATION; X-RAY; GLYCOL)-TERMINATED MONOLAYERS; DNA HYBRIDIZATION; PLATELET-ADHESION; INTERFACIAL WATER; STRONG RESISTANCE; MAMMALIAN-CELLS;
D O I
10.1038/s41428-018-0075-1
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
For a long time, water has been speculated to play an essential role in the interactions of proteins and cells with artificial biocompatible materials. The current question is how water molecules at the interfaces affect the adsorption of proteins and the adhesion of cells. To answer this question, we introduce recent works that investigated the interfacial behavior of water near self-assembled monolayers (SAMs) by different types of analytical techniques. By combining these findings, we discuss how interfacial water affects the protein and cell resistance of various bioinert SAMs.
引用
收藏
页码:563 / 571
页数:9
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