Hepatosplenic T cell lymphoma responsive to 2′-deoxycoformycin therapy

被引：15
作者：
Bennett, Michael [1 ]
Matutes, Estella [2 ]
Gaulard, Philippe [3 ]
机构：
[1] HaEmek Med Ctr, Dept Haematol, IL-18101 Afula, Israel
[2] Royal Marsden Hosp, Dept Haematol, London SW3 6JJ, England
[3] Henri Mondor Hosp, Dept Pathol, Paris, France
来源：
AMERICAN JOURNAL OF HEMATOLOGY | 2010年 / 85卷 / 09期
关键词：
GAMMA-DELTA; CLINICOPATHOLOGICAL ENTITY; HEMOPHAGOCYTIC SYNDROME; ISOCHROMOSOME; 7Q; NK-CELL; FEATURES; ABNORMALITY; EXPRESSION; ORIGIN;
D O I：
10.1002/ajh.21774
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Hepatosplenic T cell lymphoma (HSTL) is a rare condition usually with an aggresssive course and a poor prognosis even after extensive treatment. We describe here a patient who presented with hemophagocytosis. The lymphoma had unusual phenotypic features, an indolent course and responded to 2'-deoxycoformycin therapy as a single agent. We suggest that this therapy be used in further cases as part of the treatment strategy.
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收藏
页码：727 / 729
页数：3
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