New Therapies for Psoriasis

被引:5
作者
Strober, Bruce E. [1 ]
机构
[1] Univ Connecticut, Ctr Hlth, Dept Dermatol, Farmington, CT USA
关键词
Apremilast; efficacy; psoriasis; safety; secukinumab; PHOSPHODIESTERASE-4; INHIBITOR; PLAQUE PSORIASIS; PHASE-III; APREMILAST; MODERATE;
D O I
10.12788/j.sder.2016.020
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Among the newer medications for treating psoriasis are the interleukin-17A inhibitor secukinumab and the phosphodiesterase 4 inhibitor apremilast. Secukinumab offers a level of efficacy greater than that of the tumor necrosis factor-alpha inhibitor adalimumab. Apremilast is associated with lower levels of efficacy than the biologic therapies for psoriasis. Apremilast may cause diarrhea and nausea and is associated with weight loss and rare instances of depression. (C) 2016 published by Frontline Medical Communications
引用
收藏
页码:S71 / S73
页数:3
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