Cerebellar Gray Matter Volume, Executive Function, and Insomnia: Gender Differences in Adolescents

被引：29

作者：

Jung, Kyu-In ^{[1
]}

Park, Min-Hyeon ^{[1
]}

Park, Bumhee ^{[2
,6
]}

Kim, Shin-Young ^{[1
]}

Kim, Yae On ^{[1
]}

Kim, Bung-Nyun ^{[3
]}

Park, Subin ^{[4
]}

Song, Chan-Hee ^{[5
]}

机构：

[1] Catholic Univ Korea, St Pauls Hosp, Dept Psychiat, Coll Med, Seoul, South Korea

[2] Ajou Univ, Dept Biomed Informat, Sch Med, Suwon, South Korea

[3] Seoul Natl Univ, Dept Psychiat & Behav Sci, Coll Med, Seoul, South Korea

[4] Natl Ctr Mental Hlth, Dept Res Planning, Seoul, South Korea

[5] Catholic Univ Korea, Yeouido St Marys Hosp, Dept Family Med, Coll Med, Seoul, South Korea

[6] Ajou Univ, Ajou Res Inst Innovat Med, Off Biostat, Med Ctr, Suwon, South Korea

来源：

SCIENTIFIC REPORTS | 2019年 / 9卷 / 1期

基金：

新加坡国家研究基金会;

关键词：

VERBAL WORKING-MEMORY; COGNITIVE FUNCTION; BASAL GANGLIA; SLEEP DISORDERS; POOR SLEEP; BRAIN; PERFORMANCE; ACTIVATION; DEPRESSION; CHILDHOOD;

D O I：

10.1038/s41598-018-37154-w

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The cerebellum is an important region responsible for adolescent cognitive function and sleep, and their correlation is expected to show different patterns depending on age and gender. We examined the regional cerebellar gray matter volume (GMV), executive function (EF) and insomnia symptoms to identify their correlation and gender differences in adolescents. Data for a total of 55 subjects' (M = 31, F = 24, 14.80 +/- 1.39 years old) were analyzed. The correlations between cerebellar regional GMV and Wisconsin card sorting test (WCST) subcategories showed that EF was better with larger GMV both in males and females. Far more overall correlations with cerebellar regions were observed in boys, with corresponding correlation strength being higher, and differences in localization were also observed in contrast to girls. Larger cerebellar GMV corresponded to better EF in adolescents. Insomnia did not influence the correlations between cerebellar regional GMV and EF, but more severe insomnia in boys correlated to smaller GMV in the right flocculonodular lobe. These results might implicate that the adolescent cerebellum is involved differently in EF dependent on gender.

引用

页数：9

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