Sources and Sinks: A Stochastic Model of Evolution in Heterogeneous Environments

被引：49

作者：

Hermsen, Rutger ^{[1
]}

Hwa, Terence ^{[1
]}

机构：

[1] Univ Calif San Diego, Ctr Theoret Biol Phys, La Jolla, CA 92093 USA

来源：

PHYSICAL REVIEW LETTERS | 2010年 / 105卷 / 24期

基金：

美国国家科学基金会;

关键词：

BLACK-HOLE SINK; LOCAL ADAPTATION; POPULATION-DYNAMICS; ESCHERICHIA-COLI; NICHE EVOLUTION; IMMIGRATION; LANDSCAPES; RESISTANCE; HABITATS;

D O I：

10.1103/PhysRevLett.105.248104

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We study evolution driven by spatial heterogeneity in a stochastic model of source-sink ecologies. A sink is a habitat where mortality exceeds reproduction so that a local population persists only due to immigration from a source. Immigrants can, however, adapt to conditions in the sink by mutation. To characterize the adaptation rate, we derive expressions for the first arrival time of adapted mutants. The joint effects of migration, mutation, birth, and death result in two distinct parameter regimes. These results may pertain to the rapid evolution of drug-resistant pathogens and insects.

引用

页数：4

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