Synthesis of [1′-fluoro-2′,2′-bis-(hydroxymethyl)-cyclopropylmethyl]purines as antiviral agents

被引：5

作者：

Park, JH

Choi, MH

Jeong, LS

Chim, MW

Kim, HD

机构：

[1] Sookmyung Womens Univ, Coll Pharm, Seoul 140742, South Korea

[2] Ewha Womans Univ, Coll Pharm, Seoul, South Korea

[3] Seoul Natl Univ, Coll Pharm, Seoul, South Korea

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2003年 / 22卷 / 5-8期

关键词：

antiviral; cyclopropylmethyl purines; carbonucleoside;

D O I：

10.1081/NCN-120022694

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[1'-fluoro-2',2'-bis-(hydroxymethyl)cyclopropylmethyl]purines were designed, synthesized and their antiviral activity against poliovirus, HSV and HIV was evaluated.

引用

页码：955 / 957

页数：3

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[4] Design and synthesis of novel fluorocyclopropanoid nucleosides [J].

Lee, YR ;

Park, JH ;

Jeon, R ;

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NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2001, 20 (4-7) :677-679

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