Synthesis and characterization of a Zn(II) complex of a pyrazole-based ligand bearing a chiral L-alaninemethylester

被引：42

作者：

Roh, SG

Park, YC

Park, DK

Kim, TJ

Jeong, JH ^{[1
]}

机构：

[1] Kyungpook Natl Univ, Dept Chem, Taegu 702701, South Korea

[2] Kyungpook Natl Univ, Dept Ind Chem, Taegu 702701, South Korea

来源：

POLYHEDRON | 2001年 / 20卷 / 15-16期

基金：

新加坡国家研究基金会;

关键词：

crystal structures; zinc complexes; chiral N-substituted pyrazole;

D O I：

10.1016/S0277-5387(01)00788-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Reaction of ZnCl2 with a new ligand N,N-bis(3,5-dimethylpyrazolylmethyl)-L-alaninemethylester (bdmpame) in methanol gives [ZnCl2(bdmpame)]. The structure of [ZnCl2(bdmpame)]. CH2Cl2 has been resolved by X-ray crystallographic analysis. The Zn atom has a distorted tetrahedral geometry involving a nitrogen atom from each pyrazole in bdmpame and two chloro ligands with bond lengths in the range 2.037(4)-2.237(2) Angstrom. The nitrogen atom of the L-alaninemethylester group in the compound was not coordinated to the metal center, giving an eight-membered ring in which the nitrogen atoms of each pyrazole in bdmpame are coordinated to the metal center. The results of the catalytic enantioselective reduction of acetophenone promoted by ligand/Zn(OTf)(2) = 1:1 mole ratio in the presence of catecholborane for 48 h at 0 degreesC gives (S)-(-)-1-phenylethanol in 21% ee with 68% yield. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1961 / 1965

页数：5

共 47 条

[1] A MONONUCLEAR ZINC HYDROXIDE COMPLEX STABILIZED BY A HIGHLY SUBSTITUTED TRIS(PYRAZOLY)HYDROBORATO LIGAND - ANALOGIES WITH THE ENZYME CARBONIC-ANHYDRASE [J].