Topical negative-pressure wound therapy: emerging devices and techniques

被引：36

作者：

Horch, Raymund E. ^{[1
]}

Ludolph, Ingo ^{[1
]}

Mueller-Seubert, Wibke ^{[1
]}

Zetzmann, Katharina ^{[1
]}

Hauck, Theresa ^{[1
]}

Arkudas, Andreas ^{[1
]}

Geierlehner, Alexander ^{[1
]}

机构：

[1] Friedrich Alexander Univ Erlangen Nuernberg FAU, Univ Hosp Erlangen, Dept Plast & Hand Surg, Lab Tissue Engn & Regenerat Med, Erlangen, Germany

来源：

EXPERT REVIEW OF MEDICAL DEVICES | 2020年 / 17卷 / 02期

关键词：

Medical device; negative pressure wound therapy; wounds; wound coverage; wound management; future applications; VACUUM-ASSISTED CLOSURE; MICROVASCULAR BLOOD-FLOW; POST-STERNOTOMY MEDIASTINITIS; THICKNESS SKIN-GRAFTS; SUBATMOSPHERIC PRESSURE; TEMPORARY TREATMENT; SURGICAL INCISIONS; CONTROLLED-TRIAL; TISSUE PRESSURE; DIFFERENT SIZES;

D O I：

10.1080/17434440.2020.1714434

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Introduction: The treatment of chronic wounds constitutes a massive financial burden to society and our health-care system. Therefore, efficient wound care is of great importance to all kinds of medical fields. The implementation and modification of negative-pressure wound therapy can be seen as a major improvement in wound healing. Many different NPWT applications evolved trying to address various wound etiologies. Areas covered: This review aims to give an overview of various NPWT applications, show its effects on wound healing, and discuss future modifications. Expert opinion: NPWT as a delivery device for cold plasma, growth factors, or targeted stem cells to the wound bed and the ability to monitor the inflammatory activity, bacterial load and wound healing factors can be seen as possible future steps to individualized wound care. In addition, it requires high-quality experimental studies to develop the ideal foam in terms of microstructure, pore size, and material properties.

引用

页码：139 / 148

页数：10

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