Oxidative stress and aging: role of physical exercise

被引:0
|
作者
Sampaio, Ricardo Camoes [1 ]
de Moraes, Camila [2 ]
机构
[1] Univ Cruzeiro Sul, Programa Posgrad Ciencias Movimento Humano, Inst Ciencias Atividade Fis & Esportes, Sao Paulo, Brazil
[2] Escola Educ Fis & Esporte Ribeirao Preto, Ribeirao Preto, SP, Brazil
来源
MOTRIZ-REVISTA DE EDUCACAO FISICA | 2010年 / 16卷 / 02期
关键词
Reactive oxygen species; Exercise; Aging; FREE-RADICALS; NITRIC-OXIDE; VITAMIN-E; OLDER-ADULTS; LIPID-PEROXIDATION; SKELETAL-MUSCLE; ANTIOXIDANT; OXYGEN; DAMAGE; MECHANISMS;
D O I
暂无
中图分类号
G8 [体育];
学科分类号
04 ; 0403 ;
摘要
Different theories have been developed to explain the aging process and the Free-radical Theory of Aging had shown significant evidence that aging is the result of ROS toxicity action that lead to cellular DNA injury, lipid and protein oxidation. While during exercise session a major oxygen consumption increases ROS production, an adaptation occurs at cellular level and antioxidant enzymes concentration or activity are increase. Therefore, this review aims to show the mainly mechanisms of ROS generation and antioxidant defense mechanisms, as well the adaptations induced by physical exercise that act as a protection against oxidative stress related-injuries.
引用
收藏
页码:506 / 515
页数:10
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