KiT: a MATLAB package for kinetochore tracking

被引：9

作者：

Armond, Jonathan W. ^{[1
,2
,3
]}

Vladimirou, Elina ^{[1
]}

McAinsh, Andrew D. ^{[1
]}

Burroughs, Nigel J. ^{[2
,3
]}

机构：

[1] Univ Warwick, Warwick Med Sch, Div Biomed Cell Biol, Mechanochem Cell Biol Bldg, Coventry CV4 7AL, W Midlands, England

[2] Univ Warwick, Warwick Syst Biol Ctr, Coventry CV4 7AL, W Midlands, England

[3] Univ Warwick, Math Inst, Coventry CV4 7AL, W Midlands, England

来源：

BIOINFORMATICS | 2016年 / 32卷 / 12期

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1093/bioinformatics/btw087

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A Summary: During mitosis, chromosomes are attached to the mitotic spindle via large protein complexes called kinetochores. The motion of kinetochores throughout mitosis is intricate and automated quantitative tracking of their motion has already revealed many surprising facets of their behaviour. Here, we present 'KiT' (Kinetochore Tracking)-an easy-to-use, open-source software package for tracking kinetochores from live-cell fluorescent movies. KiT supports 2D, 3D and multi-colour movies, quantification of fluorescence, integrated deconvolution, parallel execution and multiple algorithms for particle localization.

引用

页码：1917 / 1919

页数：3

共 12 条

[11] Automatic fluorescent tag detection in 3D with super-resolution: application to the analysis of chromosome movement [J].

Thomann, D ;

Rines, DR ;

Sorger, PK ;

Danuser, G .

JOURNAL OF MICROSCOPY-OXFORD, 2002, 208 (01) :49-64

[12] Nonautonomous Movement of Chromosomes in Mitosis [J].

Vladimirou, Elina ;

Mchedlishvili, Nunu ;

Gasic, Ivana ;

Armond, Jonathan W. ;

Samora, Catarina P. ;

Meraldi, Patrick ;

McAinsh, Andrew D. .

DEVELOPMENTAL CELL, 2013, 27 (01) :60-71

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