Using lanthanide ions in molecular bioimaging

被引:325
作者
Amoroso, Angelo J. [1 ]
Pope, Simon J. A. [1 ]
机构
[1] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, S Glam, Wales
关键词
MRI CONTRAST AGENTS; IN-VITRO EVALUATION; MAGNETIC-RESONANCE; EUROPIUM COMPLEXES; WATER EXCHANGE; 2-PHOTON MICROSCOPY; PROTON-EXCHANGE; SPIN RELAXATION; CROSS-SECTIONS; EXCITED-STATES;
D O I
10.1039/c4cs00293h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Trivalent lanthanide ions offer remarkable opportunities in the design of bioimaging agents: this review presents an accessible discussion of their application in both optical and magnetic resonance imaging. Aspects of molecular design, control over key physical properties and biological compatibility are discussed in this context, together with developments and opportunities as responsive probes and in multimodal imaging.
引用
收藏
页码:4723 / 4742
页数:20
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