Using lanthanide ions in molecular bioimaging

被引：325

作者：

Amoroso, Angelo J. ^{[1
]}

Pope, Simon J. A. ^{[1
]}

机构：

[1] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, S Glam, Wales

来源：

CHEMICAL SOCIETY REVIEWS | 2015年 / 44卷 / 14期

关键词：

MRI CONTRAST AGENTS; IN-VITRO EVALUATION; MAGNETIC-RESONANCE; EUROPIUM COMPLEXES; WATER EXCHANGE; 2-PHOTON MICROSCOPY; PROTON-EXCHANGE; SPIN RELAXATION; CROSS-SECTIONS; EXCITED-STATES;

D O I：

10.1039/c4cs00293h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Trivalent lanthanide ions offer remarkable opportunities in the design of bioimaging agents: this review presents an accessible discussion of their application in both optical and magnetic resonance imaging. Aspects of molecular design, control over key physical properties and biological compatibility are discussed in this context, together with developments and opportunities as responsive probes and in multimodal imaging.

引用

页码：4723 / 4742

页数：20

共 91 条

[1] Highly sensitive MRI chemical exchange saturation transfer agents using liposomes [J].

Aime, S ;

Delli Castelli, D ;

Terreno, E .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (34) :5513-5515

[2]

Aime S, 2002, ANGEW CHEM INT EDIT, V41, P4334, DOI 10.1002/1521-3773(20021115)41:22<4334::AID-ANIE4334>3.0.CO

[3]

2-1

[4] Nuclear magnetic resonance, luminescence and structural studies of lanthanide complexes with octadentate macrocyclic ligands bearing benzylphosphinate groups [J].

Aime, S ;

Batsanov, AS ;

Botta, M ;

Dickins, RS ;

Faulkner, S ;

Foster, CE ;

Harrison, A ;

Howard, JAK ;

Moloney, JM ;

Norman, TJ ;

Parker, D ;

Royle, L ;

Williams, JAG .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1997, (19) :3623-3636

[5] A macromolecular Gd(III) complex as pH-responsive relaxometric probe for MRI applications [J].

Aime, S ;

Botta, M ;

Crich, SG ;

Giovenzana, G ;

Palmisano, G ;

Sisti, M .

CHEMICAL COMMUNICATIONS, 1999, (16) :1577-1578

[6] Responsive, di-metallic lanthanide complexes of a piperazine-bridged bis-macrocyclic ligand: modulation of visible luminescence and proton relaxivity [J].

Andrews, Michael ;

Amoroso, Angelo J. ;

Harding, Lindsay P. ;

Pope, Simon J. A. .

DALTON TRANSACTIONS, 2010, 39 (14) :3407-3411

[7]

Anelli PL, 2000, EUR J INORG CHEM, P625

[8] Luminescence imaging microscopy and lifetime mapping using kinetically stable lanthanide(III) complexes [J].

Beeby, A ;

Botchway, SW ;

Clarkson, IM ;

Faulkner, S ;

Parker, AW ;

Parker, D ;

Williams, JAG .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2000, 57 (2-3) :83-89

[9] Non-radiative deactivation of the excited states of europium, terbium and ytterbium complexes by proximate energy-matched OH, NH and CH oscillators: an improved luminescence method for establishing solution hydration states [J].

Beeby, A ;

Clarkson, IM ;

Dickins, RS ;

Faulkner, S ;

Parker, D ;

Royle, L ;

de Sousa, AS ;

Williams, JAG ;

Woods, M .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1999, (03) :493-503

[10] First bodipy-DOTA derivatives as probes for bimodal imaging [J].

Bernhard, Claire ;

Goze, Christine ;

Rousselin, Yoann ;

Denat, Franck .

CHEMICAL COMMUNICATIONS, 2010, 46 (43) :8267-8269

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