A direct route to a new class of acrylamide thioglycosides

被引：13

作者：

Elgemeie, Galal H. ^{[1
]}

Zaghary, Wafaa A. ^{[2
]}

Amin, Kamelia M. ^{[3
]}

Nasr, Tamer M. ^{[2
]}

机构：

[1] Helwan Univ, Dept Chem, Fac Sci, Cairo, Egypt

[2] Helwan Univ, Dept Pharmaceut Chem, Fac Pharm, Cairo, Egypt

[3] Cairo Univ, Dept Pharmaceut Chem, Fac Pharm, Cairo, Egypt

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 2008年 / 27卷 / 06期

关键词：

acrylamide thioglycosides; potassium 2-cyanoethylene-1-thiolate salts; 5-aminopyrazoles;

D O I：

10.1080/07328300802262786

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The preparation of a new class of acrylamide thioglycosides via one-pot reaction of the potassium 2-cyanoethylene-1-thiolate salts with 2,3,4,6-tetra-O-acetyl--D-gluco- and galactopyranosyl bromides has been studied. The E-configuration of these thioglycosides was proven by their transformations to the corresponding 5-aminopyrazoles.

引用

页码：373 / 378

页数：6

共 7 条

[1] Synthesis and anti-HIV activity of different novel nonclassical nucleosides [J].