Neuroimmunological response in neuro-Behcet's

被引：2

作者：

Alejandro Garcia-Rivero, Alexis ^{[1
]}

Gonzalez-Argote, Javier ^{[1
]}

Martinez Larrart, Jose Pedro ^{[2
]}

Iglesias Gonzalez, Ivonne Margarita ^{[2
]}

Juan Dorta-Contreras, Alberto ^{[2
]}

机构：

[1] Univ Ciencias Med La Habana, Inst Ciencias Basicas & Predin Victoria Giron, Havana, Cuba

[2] Univ Ciencias Med La Habana, Fac Ciencias Med Miguel Enriquez, Lab Cent Liquido Cefalorraquideo LABCEL, Havana, Cuba

来源：

REUMATOLOGIA CLINICA | 2019年 / 15卷 / 02期

关键词：

Bloodcerebrospinal fluid barrier; Behcet's disease; Immunoglobulins; Neuro-Behcet's disease; Reibergram; Intrathecal synthesis;

D O I：

10.1016/j.reuma.2017.02.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Behcet's disease is a chronic, multisystem, autoimmune vasculitis characterised by a triad of key signs. We report the case of a 16-year-old Caucasian girl, who complained of headache, dizziness and paresis of the left side of her body. After physical examination and ancillary tests, she was diagnosed with Behcet's disease with neurological manifestations (neuro-Behcet's disease). She had a good response to treatment. IgG, IgA, IgM and albumin were quantified in serum and cerebrospinal fluid by single radial immunodiffusion. Intrathecal synthesis was found for the three classes of immunoglobulins. This is the first case in which the Reibergram was used to evaluate the neuroimmunological response in a patient with Behcet's disease, suggesting the use of this diagnostic means for the active phase of the disease. (C) 2017 Elsevier Espana, S.L.U. and Sociedad Espanola de Reumatologia y Colegio Mexicano de Reumatologia. All rights reserved.

引用

页码：117 / 120

页数：4

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