Accurate and Rapid Estimation of Phosphene Thresholds (REPT)

被引：28

作者：

Abrahamyan, Arman ^{[1
]}

Clifford, Colin W. G. ^{[1
]}

Ruzzoli, Manuela ^{[2
]}

Phillips, Dan ^{[3
]}

Arabzadeh, Ehsan ^{[4
]}

Harris, Justin A. ^{[1
]}

机构：

[1] Univ Sydney, Sch Psychol, Sydney, NSW 2006, Australia

[2] IRCCS San Giovanni Dio Fatebenefratelli, Cognit Neurosci Sect, Brescia, Italy

[3] Magstim Co Ltd, Whitland, Wales

[4] Univ New S Wales, Sch Psychol, Sydney, NSW, Australia

来源：

PLOS ONE | 2011年 / 6卷 / 07期

基金：

澳大利亚研究理事会;

关键词：

TRANSCRANIAL MAGNETIC STIMULATION; HUMAN VISUAL-CORTEX; MOTOR THRESHOLD; CORTICAL EXCITABILITY; PSYCHOMETRIC FUNCTION; BRAIN; CONTRAST; DISSOCIATION; DISTANCE; AREA;

D O I：

10.1371/journal.pone.0022342

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

To calibrate the intensity of transcranial magnetic stimulation (TMS) at the occipital pole, the phosphene threshold is used as a measure of cortical excitability. The phosphene threshold (PT) refers to the intensity of magnetic stimulation that induces illusory flashes of light (phosphenes) on a proportion of trials. The existing PT estimation procedures lack the accuracy and mathematical rigour of modern threshold estimation methods. We present an improved and automatic procedure for estimating the PT which is based on the well-established Psi Bayesian adaptive staircase approach. To validate the new procedure, we compared it with another commonly used procedure for estimating the PT. We found that our procedure is more accurate, reliable, and rapid when compared with an existing PT measurement procedure. The new procedure is implemented in Matlab and works automatically with the Magstim Rapid(2) stimulator using a convenient graphical user interface. The Matlab program is freely available for download.

引用

页数：8

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