Impact of pre-pregnancy body mass index and gestational weight gain on the risk of maternal and infant pregnancy complications in Korean women

被引：25

作者：

Choi, Hansol ^{[1
]}

Lim, Joong-Yeon ^{[2
]}

Lim, Nam-Kyoo ^{[1
]}

Ryu, Hyun Mee ^{[3
]}

Kwak, Dong Wook ^{[4
]}

Chung, Jin Hoon ^{[5
]}

Park, Hee Jin ^{[6
]}

Park, Hyun-Young ^{[7
]}

机构：

[1] Korea Natl Inst Hlth, Korea Dis Control & Prevent Agcy, Div Populat Res, Dept Precis Med, Cheongju, South Korea

[2] Minist Hlth & Welf, Bur Adv Hlth Technol Policy, Div Healthcare Technol Dev, Sejong, South Korea

[3] CHA Univ Sch Med, Dept Obstet & Gynecol, CHA Bundang Med Ctr, Seongnam, South Korea

[4] Ajou Univ, Sch Med, Dept Obstet & Gyneco, Suwon, South Korea

[5] Univ Ulsan, Sch Med, Asan Med Ctr, Dept Obstet & Gynecol, Seoul, South Korea

[6] CHA Univ Sch Med, CHA Gangnam Med Ctr, Department Obstet & Gynecol, Seoul, South Korea

[7] Korea Natl Inst Hlth, Korea Dis Control & Prevent Agcy, Dept Precis Med, Cheongju, South Korea

来源：

INTERNATIONAL JOURNAL OF OBESITY | 2022年 / 46卷 / 01期

关键词：

METABOLIC SYNDROME; SMOKING-CESSATION; OBESE WOMEN; OUTCOMES; ASSOCIATION; PREVALENCE; CLASSIFICATION; HYPERGLYCEMIA; DEPRESSION; ADIPOSITY;

D O I：

10.1038/s41366-021-00946-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background/Objective Healthy weight maintenance before and during pregnancy has a significant effect on pregnancy outcomes; however, there are no specific guidelines for gestational weight gain in pregnant Korean women. Therefore, we investigated the impact of pre-pregnancy body mass index (BMI) and gestational weight gain on the risk of maternal and infant pregnancy complications in pregnant Korean women. Methods Study participants comprised 3454 singleton pregnant women from the Korean Pregnancy Outcome Study who had baseline examination and pregnancy outcome data. Maternal pre-pregnancy BMI and gestational weight gain were categorized according to the Asia-pacific regional guidelines and the Institute of Medicine recommendations, respectively. The primary outcome was any adverse outcomes, defined as the presence of one or more of the following: hypertensive disorders of pregnancy, gestational diabetes mellitus, peripartum depressive symptom, cesarean delivery, delivery complications, preterm birth, small or large weight infant, neonatal intensive care unit admission, or a congenital anomaly. Multiple logistic regression models were applied to examine the independent and combined impact of pre-pregnancy BMI and gestational weight gain on the risk of maternal and infant outcomes. Results Obesity before pregnancy significantly increased the risk of perinatal adverse outcomes by more than 2.5 times [odds ratio (OR): 2.512, 95% confidence interval (CI): 1.817-3.473]. Compared to that in women with appropriate gestational weight gain, women with excessive weight gain had a 36.4% incremental increase in the risk of any adverse outcomes [OR: 1.364, 95% CI: 1.115-1.670]. Moreover, women who were overweight or obese before pregnancy and had excessive gestational weight gain had a three-fold increase in the risk of adverse outcomes [OR: 3.460, 95% CI: 2.210-5.417]. Conclusion This study highlights the need for appropriate weight recommendations before and during pregnancy to prevent perinatal complications in Korean women of childbearing age.

引用

页码：59 / 67

页数：9

共 53 条

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