Influence of haemodialysis on high-sensitivity C-reactive protein, lipoprotein(a), apolipoproteins A and B

被引:2
作者
Lippi, Giuseppe
Tessitore, Nicola
Salvagno, Gian Luca
Bedogna, Valeria
Bassi, Antonella
Montagnana, Martina
Lupo, Antonio
Guidi, Gian Cesare
机构
[1] Univ Verona, Dipartimento Sci Morfol Biomed, Sezione Chim Clin, I-37121 Verona, Italy
[2] Univ Verona, Dipartimento Sci Biomed & Chirug, Sez Nefrol, I-37100 Verona, Italy
关键词
high-sensitivity C-reactive protein; chronic renal failure; haemodialysis; apolipoprotein; lipoprotein(a);
D O I
10.1016/j.clinbiochem.2007.07.007
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Objectives: There is debate on the influence of haemodialysis (HD) on lipoprotein(a). Design and methods: Lp(a), apo A, apo B and high-sensitivity C-reactive protein (hs-CRP) were measured in 46 patients pre- and post-HD. Results: The median Lp(a) concentration significantly decreased post-HD (106 vs. 145 mg/L, p<0.001). No significant variations were observed for apo A, apo B and hs-CRP. Comparable results were observed with high- and low-flux membranes. Conclusion: HD is effective in lowering Lp(a). (C) 2007 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:1336 / 1338
页数:3
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