Evaluation of Right Ventricular Regional Volume and Systolic Function in Patients with Pulmonary Arterial Hypertension Using Three-Dimensional Echocardiography

被引:22
作者
Kong, Dehong [1 ]
Shu, Xianhong [1 ]
Pan, Cuizhen [1 ]
Cheng, Leilei [1 ]
Dong, Lili [1 ]
Yao, Haohua [1 ]
Zhou, Daxin [2 ]
机构
[1] Fudan Univ, Shanghai Inst Cardiovasc Dis, Dept Echocardiog, Zhongshan Hosp, Shanghai 200032, Peoples R China
[2] Fudan Univ, Shanghai Inst Cardiovasc Dis, Dept Cardiol, Zhongshan Hosp, Shanghai 200032, Peoples R China
来源
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES | 2012年 / 29卷 / 06期
基金
中国国家自然科学基金;
关键词
three-dimensional echocardiography; right ventricular; systolic function; regional; pulmonary arterial hypertension; HEART-FAILURE; VARIABILITY; PERFORMANCE; ACCURACY; STRAIN; ECHO;
D O I
10.1111/j.1540-8175.2012.01681.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To evaluate right ventricular (RV) regional volume and systolic function in patients with pulmonary arterial hypertension (PAH) using real time three-dimensional echocardiography (RT3DE), and to explore the relationship between parameters measured by RT3DE and right heart catheterization (RHC). Methods: RT3DE images were acquired from 24 patients with PAH and 27 normal controls for evaluation and analysis to obtain RV regional end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF) in three compartments (inflow, body, and outflow). Conventional echocardiographic parameters were calculated and recorded. RHC was performed in 17 patients to obtain pulmonary artery systolic pressure (PASP) and pulmonary vascular resistance (PVR). Results: RV regional EDV and ESV were significantly higher while regional EF was significantly lower in the PAH patients when compared with controls (P < 0.001). In the PAH group, EDV was similar in the inflow and body compartment, both higher than that in the outflow compartment (P < 0.05); EF was the highest in the inflow compartment and the lowest in the body compartment (P < 0.05). RV regional EF in the inflow compartment and global EF were negatively correlated with PASP (r =0.766, 0.816, P < 0.001) and PVR (r =0.529, 0.656, P < 0.05). Conclusions: In patients with PAH, RV regional volume was enlarged and systolic function was impaired with distinct characteristics; regional EF in the inflow compartment and global EF were inversely correlated with PASP and PVR. Evaluation of RV regional systolic function using RT3DE may play a potential role in the noninvasive assessment of the severity of PAH. (Echocardiography 2012;29:706-712)
引用
收藏
页码:706 / 712
页数:7
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