Identification of Three Novel HIV-1 Second-Generation Recombinant Forms (CRF01_AE/CRF07_BC) Among Men Who Have Sex with Men in Baoding, Hebei, China

被引：0
作者：
Fan, Weiguang [1 ]
Liu, Yang [1 ]
Li, Yan [1 ]
Su, Miaomiao [2 ]
Meng, Juan [2 ]
Lu, Xinli [3 ]
Shi, Penghui [1 ]
机构：
[1] Peoples Hosp Baoding, Dept Clin Lab Med, 608 Dongfeng East Rd, Baoding 071000, Peoples R China
[2] Peoples Hosp Baoding, Dept Infect Div, Baoding, Peoples R China
[3] Hebei Prov Ctr Dis Control & Prevent, Dept AIDS Res, Hebei Key Lab Pathogen & Epidemiol Infect Dis, Shijiazhuang, Hebei, Peoples R China
来源：
AIDS RESEARCH AND HUMAN RETROVIRUSES | 2022年 / 38卷 / 10期
关键词：
CRF01_AE; CRF07_BC; HIV; MSM; Baoding;
D O I：
10.1089/aid.2022.0037
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The number of the second-generation recombinants originated from these two subtypes is significantly increasing due to co-circulating of CRF01_AE and CRF07_BC in China, especially among men who have sex with men (MSM). In this study, we reported three new unique recombinant forms (URFs) among MSM in Baoding, China. Phylogenetic and recombinant analyses based on the near full-length genome revealed these three URFs were the second-generation recombinant strains originated from CRF01_AE and CRF07_BC. Nowadays, the MSM has become a main route that causes the viral recombination. Therefore, the further epidemiological surveillance should be conducted in the MSM population to strengthen our knowledge of HIV-1 evolution and genetic diversity.
引用
收藏
页码：812 / 816
页数：5
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