Synthesis and structure of potential Lewis acid-Lewis base bifunctional catalysts:: 1-N,N-dimethylamino-8-borononaphthalene derivatives

被引：49
作者：
Giles, RL
Howard, JAK
Patrick, LGF
Probert, MR
Smith, GE
Whiting, A
机构：
[1] Univ Durham, Dept Chem, Sci Labs, Durham DH1 3LE, England
[2] GlaxoSmithKline Res & Dev Ltd, Tonbridge TN11 9AN, Kent, England
来源：
JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2003年 / 680卷 / 1-2期
基金：
英国工程与自然科学研究理事会;
关键词：
metallation; atylamine; arylboronate; boronic acids; aryldiffiloroborane; NMR; X-ray;
D O I：
10.1016/S0022-328X(03)00399-1
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A new series of boronate-amine substituted potential bifunctional catalysts have been prepared by directed lithiation of 1-N,N-dimethylnaphthalene, followed by reaction borate esters. Both diisopropyl and pincacol ester derivatives of the resulting boronates were prepared, together with a novel boroxine which shows novel N-B interactions in the crystal structure. The corresponding dimethyl-[8-(difluoroborolyl)-naphthalen-1-yl]-amine was directly accessed from the boroxine by reaction with potassium hydrogen fluoride. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：257 / 262
页数：6
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