Activation of the HDC/histamine axis by reintroduction of mast cells or histamine treatment induces hepatobiliary damage, liver inflammation and fibrosis in Mdr2-/-/HDC-/- double knockout mice

被引：0
|
作者：
Hargrove, Laura [2 ]
Demieville, Jennifer [1 ]
Kennedy, Lindsey [1 ,2 ]
Thomson, Joanne [1 ]
Stephenson, Kristen [3 ]
Francis, Heather L. [1 ,2 ]
机构：
[1] Cent Texas Vet Hlth Care Syst, Temple, TX USA
[2] Texas A&M Univ, HSC, COM, Temple, TX USA
[3] Baylor Scott & Whtie, Temple, TX USA
来源：
HEPATOLOGY | 2017年 / 66卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
146
引用
收藏
页码：101A / 102A
页数：2
相关论文
共 13 条
  • [11] Prolonged usage of H1 or H2 histamine receptor antagonists decreases fibrosis and liver damage in MDR2-/- mice: novel evidence of the therapeutic benefits of anti-histamines
    Jones, Hannah
    Hargrove, Laura
    Kennedy, Lindsey
    Owens, Jennifer
    Francis, Heather L.
    HEPATOLOGY, 2015, 62 : 618A - 618A
  • [12] Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2-/- mice
    Meadows, Vik
    Kennedy, Lindsey
    Hargrove, Laura
    Demieville, Jennifer
    Meng, Fanyin
    Virani, Shohaib
    Reinhart, Evan
    Kyritsi, Konstantina
    Invernizzi, Pietro
    Yang, Zhihong
    Wu, Nan
    Liangpunsakul, Suthat
    Alpini, Gianfranco
    Francis, Heather
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2019, 1865 (12):
  • [13] TREATMENT WITH MELATONIN OR DARK THERAPY DECREASES MAST CELL (MC) ACTIVATION BY DOWNREGULATION OF MIR-200B-DEPENDENT HISTAMINE (HA) SIGNALING IN MDR2-/- MICE: A NOVEL SCENARIO FOR PSC MANAGEMENT
    Chen, Lixian
    Wu, Nan
    Glaser, Shannon S.
    Ceci, Ludovica
    Liangpunsakul, Suthat
    Yang, Zhihong
    Kennedy, Lindsey
    Meng, Fanyin
    Meadows, Vik
    Kundu, Debjyoti
    Alpini, Gianfranco
    Francis, Heather L.
    GASTROENTEROLOGY, 2020, 158 (06) : S1266 - S1266
12