Tests to determine LC50 and discriminating doses for macrocyclic lactones against the cattle tick, Boophilus microplus

被引：105

作者：

Sabatini, GA

Kemp, DH

Hughes, S

Nari, A

Hansen, J

机构：

[1] CSIRO, Long Pocket Labs, Indooroopilly, Qld 4068, Australia

[2] Univ Estadual Paulista, CPPAR, Jaboticabal, Brazil

[3] FAO, Anim Prod & Hlth Div, I-00100 Rome, Italy

来源：

VETERINARY PARASITOLOGY | 2001年 / 95卷 / 01期

关键词：

Boophilus microplus; macrocyclic lactones; resistance tests;

D O I：

10.1016/S0304-4017(00)00406-4

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Laboratory tests were carried out on larvae and adults of the cattle tick Boophilus microplus to determine the toxicity of macrocyclic lactone acaricides (MLs). Technical and commercial MLs were used in larval packet test (LPT), larval immersion test (LIT) and adult immersion test (AIT). Tn LIT and AIT the toxicity of MLs was much higher than for LPT. In the AIT, diluting the injectable formulation of MLs in water was as effective as dilution in ethanol + Triton X-100. LC50, LC99.9 and 95% confidence limits were determined so that a discriminating dose (DD) could be set for larval and adult tests in order to diagnose potential resistance to MLs in field samples of the tick. These DDs are for Australian strains of B. microplus and may not be suitable for other strains until further work is carried out. The value of these diagnostic tests can only be verified if or when resistance to MLs emerges in ticks. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：53 / 62

页数：10

共 14 条

[1]

[Anonymous], P 23 WORLD VET C MON

[2]

[Anonymous], NEW GENERATION VACCI

[3]

Benavides OE, 1999, MEM 4 SEM INT PAR PU, P260

[4]

BENAVIDES OE, 1999, P 5 BIENN C SOC TROP

[5] BOOPHILUS-ANNULATUS AND B-MICROPLUS - LABORATORY TESTS OF INSECTICIDES [J].

DRUMMOND, RO ;

ERNST, SE ;

TREVINO, JL ;

GLADNEY, WJ ;

GRAHAM, OH .

JOURNAL OF ECONOMIC ENTOMOLOGY, 1973, 66 (01) :130-133

[6] Picrotoxin blockade of invertebrate glutamate-gated chloride channels: Subunit dependence and evidence for binding within the pore [J].

Etter, A ;

Cully, DF ;

Liu, KK ;

Reiss, B ;

Vassilatis, DK ;

Schaeffer, JM ;

Arena, JP .

JOURNAL OF NEUROCHEMISTRY, 1999, 72 (01) :318-326

[7]

*FAO, 1984, TICKS TICK BORNE DIS, V1

[8]

*FAO, 1997, RECOMM FAO PAN EXP P

[9] RESISTANCE OF CATTLE TICK (BOOPHILUS-MICROPLUS (CANESTRINI)) TO BENZENE HEXACHLORIDE [J].

HITCHCOCK, LF .

AUSTRALIAN JOURNAL OF AGRICULTURAL RESEARCH, 1953, 4 (03) :360-364

[10] INSECTICIDES AND ACARICIDES - RESISTANCE AND ENVIRONMENTAL-IMPACT [J].

KUNZ, SE ;

KEMP, DH .

REVUE SCIENTIFIQUE ET TECHNIQUE DE L OFFICE INTERNATIONAL DES EPIZOOTIES, 1994, 13 (04) :1249-1286

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