Improved accuracy and phasing of lamellar neutron diffraction data by real-time swelling series method

被引：3

作者：

Bradshaw, JP

Darkes, MJM

Davies, SMA

机构：

[1] Univ Edinburgh, Royal Dick Sch Vet Studies, Dept Preclin Vet Sci, Edinburgh EH9 1QH, Midlothian, Scotland

[2] Univ Edinburgh, Sch Med, Dept Biochem, Edinburgh EH8 9XD, Midlothian, Scotland

来源：

PHYSICA B | 1997年 / 241卷

关键词：

neutron diffraction; phospholipid; phase assignment;

D O I：

10.1016/S0921-4526(97)00807-7

中图分类号：

O469 [凝聚态物理学];

学科分类号：

070205 ;

摘要：

The analytic continuation method has been widely used to phase Bragg reflections from lamellar samples of phospholipids. Here we describe its application to neutron diffraction data, collected from liquid-crystalline (L-alpha phase) samples of 1,2-dioleoyl-sn-glycero-phosphocholine (DOPC) under a state of shifting lamellar spacing. To provide a comparison with the more normal neutron approach of isotopic substitution using 2H(2)O, data were collected from similar samples, using the same experimental and optical conditions. We compare the two methods in terms of accuracy of structure factor determination, unambiguity of phase assignment and ease of use. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：1115 / 1121

页数：7

共 6 条

[1] NEUTRON-DIFFRACTION REVEALS THE SITE OF AMANTADINE BLOCKADE IN THE INFLUENZA-A M2 ION-CHANNEL [J].