GFP-inspired fluorescent polymer

被引:28
作者
Deng, Hongping [1 ,2 ]
Zhu, Qi [1 ]
Wang, Dali [1 ]
Tu, Chunlai [1 ]
Zhu, Bangshang [2 ]
Zhu, Xinyuan [1 ,2 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China
[2] Shanghai Jiao Tong Univ, Instrumental Anal Ctr, Shanghai 200240, Peoples R China
基金
中国国家自然科学基金;
关键词
PROTEIN CHROMOPHORE; DERIVATIVES; LIGHT;
D O I
10.1039/c2py20223a
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Inspired by the green fluorescent protein (GFP), a novel amphiphilic fluorescent polymer was designed and synthesized. The amphiphilic polymer showed enhanced fluorescent properties after self-assembly into micellar aggregates. Moreover, the fluorescence enhancement behavior of the GFP-inspired polymer through self-assembly was successfully applied in cell imaging.
引用
收藏
页码:1975 / 1977
页数:3
相关论文
共 23 条
[1]   Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral [J].
Baird, GS ;
Zacharias, DA ;
Tsien, RY .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (22) :11984-11989
[2]   Inhibition of twisting of a green fluorescent protein-like chromophore by metal complexation [J].
Baldridge, Anthony ;
Solntsev, Kyril M. ;
Song, Charles ;
Tanioka, Tatsuro ;
Kowalik, Janusz ;
Hardcastle, Kenneth ;
Tolbert, Laren M. .
CHEMICAL COMMUNICATIONS, 2010, 46 (31) :5686-5688
[3]   Activation of Fluorescent Protein Chromophores by Encapsulation [J].
Baldridge, Anthony ;
Samanta, Shampa R. ;
Jayaraj, Nithyanandhan ;
Ramamurthy, V. ;
Tolbert, Laren M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (05) :1498-+
[4]   Ortho green fluorescence protein synthetic chromophore; Excited-state intramolecular proton transfer via a seven-membered-ring hydrogen-bonding system [J].
Chen, Kew-Yu ;
Cheng, Yi-Ming ;
Lai, Cheng-Hsuan ;
Hsu, Cheng-Chih ;
Ho, Mei-Lin ;
Lee, Gene-Hsiang ;
Chou, Pi-Tai .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (15) :4534-+
[5]   A microwave-assisted stereoselective synthesis of polyandrocarpamines A and B [J].
Davis, Rohan A. ;
Baron, Paul S. ;
Neve, Juliette E. ;
Cullinane, Carleen .
TETRAHEDRON LETTERS, 2009, 50 (08) :880-882
[6]   The meta-green fluorescent protein chromophore [J].
Dong, Jian ;
Solntsev, Kyril M. ;
Poizat, Olivier ;
Tolbert, Laren M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (33) :10084-+
[7]   Solvatochromism of the green fluorescence protein chromophore and its derivatives [J].
Dong, Jian ;
Solntsev, Kyril M. ;
Tolbert, Laren M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (37) :12038-12039
[8]   The Green Journey [J].
Haldar, Sourav ;
Chattopadhyay, Amitabha .
JOURNAL OF FLUORESCENCE, 2009, 19 (01) :1-2
[9]   Synthesis and spectroscopic studies of model red fluorescent protein chromophores [J].
He, X ;
Bell, AF ;
Tonge, PJ .
ORGANIC LETTERS, 2002, 4 (09) :1523-1526
[10]   WAVELENGTH MUTATIONS AND POSTTRANSLATIONAL AUTOXIDATION OF GREEN FLUORESCENT PROTEIN [J].
HEIM, R ;
PRASHER, DC ;
TSIEN, RY .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (26) :12501-12504