Nanoporous Gold Electrode for Electrochemical Sensors in Biological Environment

This work describes the use of nanoporous gold as an electrode material for biosensing applications. Nanoporous gold electrodes are fabricated, and their electrochemical performance is compared to plain gold electrodes of similar dimensions. For the detection of potassium ferricyanide, the nanoporous gold electrodes show improved sensitivity and higher currents compared to planar gold electrodes. Furthermore, the nanoporous electrodes show slower adsorption kinetics and maintain a significantly higher active electrochemical surface area in the presence of fragmented amyloid beta proteins. (C) 2011 Published by Elsevier Ltd.