Nanoporous Gold Electrode for Electrochemical Sensors in Biological Environment

被引：12
|
作者：
Summerlot, David [1 ]
Kumar, Amit [1 ]
Das, Soumen [1 ]
Goldstein, Lee [3 ]
Seal, Sudipta [1 ]
Diaz, Diego [2 ]
Cho, Hyoung J. [1 ]
机构：
[1] Univ Cent Florida, AMPAC, Orlando, FL 32816 USA
[2] Univ Cent Florida, Dept Chem, Orlando, FL 32816 USA
[3] Boston Univ, Sch Med, Mol Aging & Dev Lab Photon Ctr, Boston, MA USA
来源：
EUROSENSORS XXV | 2011年 / 25卷
基金：
美国国家科学基金会;
关键词：
Nanoporous gold; Biosensensors; Electrochemical Sensors; Potassium ferricyanide; Biofouling; Amyloid beta proteins;
D O I：
10.1016/j.proeng.2011.12.360
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
This work describes the use of nanoporous gold as an electrode material for biosensing applications. Nanoporous gold electrodes are fabricated, and their electrochemical performance is compared to plain gold electrodes of similar dimensions. For the detection of potassium ferricyanide, the nanoporous gold electrodes show improved sensitivity and higher currents compared to planar gold electrodes. Furthermore, the nanoporous electrodes show slower adsorption kinetics and maintain a significantly higher active electrochemical surface area in the presence of fragmented amyloid beta proteins. (C) 2011 Published by Elsevier Ltd.
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页数：4
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