Additive manufacturing of biomaterials

被引：477

作者：

Bose, Susmita ^{[1
]}

Ke, Dongxu ^{[1
]}

Sahasrabudhe, Himanshu ^{[1
]}

Bandyopadhyay, Amit ^{[1
]}

机构：

[1] Washington State Univ, Sch Mech & Mat Engn, WM Keck Biomed Mat Res Lab, Pullman, WA 99164 USA

来源：

PROGRESS IN MATERIALS SCIENCE | 2018年 / 93卷

基金：

美国国家卫生研究院;

关键词：

Additive manufacturing/3D printing; Bioceramics; Metallic biomaterials; Biopolymers; Drug delivery; Tissue engineering; SOLID FREEFORM FABRICATION; TRICALCIUM PHOSPHATE SCAFFOLDS; TISSUE ENGINEERING SCAFFOLDS; BIOACTIVE GLASS SCAFFOLDS; CALCIUM POLYPHOSPHATE STRUCTURES; 3-DIMENSIONAL FIBER-DEPOSITION; BONE SUBSTITUTE APPLICATIONS; FREE-FORM FABRICATION; IN-VIVO OSTEOGENESIS; MECHANICAL-PROPERTIES;

D O I：

10.1016/j.pmatsci.2017.08.003

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Biomaterials are used to engineer functional restoration of different tissues to improve human health and the quality of life. Biomaterials can be natural or synthetic. Additive manufacturing (AM) is a novel materials processing approach to create parts or prototypes layer-by-layer directly from a computer aided design (CAD) file. The combination of additive manufacturing and biomaterials is very promising, especially towards patient specific clinical applications. Challenges of AM technology along with related materials issues need to be realized to make this approach feasible for broader clinical needs. This approach is already making a significant gain towards numerous commercial biomedical devices. In this review, key additive manufacturing methods are first introduced followed by AM of different materials, and finally applications of AM in various treatment options. Realization of critical challenges and technical issues for different AM methods and biomaterial selections based on clinical needs are vital. Multidisciplinary research will be necessary to face those challenges and fully realize the potential of AM in the coming days. (C) 2017 Published by Elsevier Ltd.

引用

页码：45 / 111

页数：67

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