Optimization Analyses of Functional MR Imaging of Motor Areas in Preoperative Patients

Increasingly, fMRI is used for preoperative diagnosis of patients. This method gives the possibility to locate the relevant functional areas of the brain responsible for movement, sensation and speech, which are often adjacent to the tumor. The ultimate success of any experimental fMRI depends not only on the quality of the collected image data but also appropriate selection of the parameters (Gaussian kernel, level of significance, extent threshold) so as to maximize statistical power. Our fMRI analysis carried out in SPM 12 package for the 5 patients with lesions have shown that increasing the value of clinical diagnosis requires an individual approach taking into account a given pathology and the possible implications for surgical intervention. The values of parameters which could be taken as preliminary to analyze of activations of motor cortex -primary (M1) and supplementary (SMA) are discussed.