Recent Advances in Functional Carbon Quantum Dots for Antitumour

被引:24
作者
Cai, Rong [1 ]
Xiao, Long [1 ]
Liu, Meixiu [1 ]
Du, Fengyi [2 ]
Wang, Zhirong [1 ]
机构
[1] Nanjing Univ Chinese Med, Zhangjiagang TCM Hosp, Cent Lab, Suzhou 215600, Jiangsu, Peoples R China
[2] Sch Med, Zhenjiang 212013, Jiangsu, Peoples R China
关键词
CQDs; antitumour; drug delivery; phototherapy; CELL LUNG-CANCER; PHOTODYNAMIC THERAPY; DRUG-DELIVERY; IN-VITRO; HYDROTHERMAL SYNTHESIS; LIPOSOMAL DOXORUBICIN; SELECTIVE DETECTION; FLUORESCENT-PROBES; HIGHLY FLUORESCENT; MESOPOROUS SILICA;
D O I
10.2147/IJN.S334012
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in biomedical fields. CQDs can be fabricated by "top-down" and "bottom-up" methods, both of which involve oxidation, carbonization, pyrolysis and polymerization. The functions of CQDs include biological imaging, biosensing, drug delivery, gene carrying, antimicrobial performance, photothermal ablation and so on, which enable them to be utilized in antitumour applications. The purpose of this review is to summarize the research progress of CQDs in antitumour applications from preparation and characterization to application prospects. Furthermore, the challenges and opportunities of CQDs are discussed along with future perspectives for precise individual therapy of tumours.
引用
收藏
页码:7195 / 7229
页数:35
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