Care of the Child With Ebola Virus Disease

被引：13
作者：
Eriksson, Carl O. [1 ]
Uyeki, Timothy M. [2 ]
Christian, Michael D. [3 ]
King, Mary A. [4 ,5 ]
Braner, Dana A. V. [1 ]
Kanter, Robert K. [6 ,7 ]
Kissoon, Niranjan [8 ,9 ]
机构：
[1] Oregon Hlth & Sci Univ, Dept Pediat, Div Pediat Crit Care, Portland, OR 97201 USA
[2] US Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA
[3] Mt Sinai Hosp, Dept Crit Care, Toronto, ON M5G 1X5, Canada
[4] Seattle Childrens Hosp, Seattle, WA USA
[5] Univ Washington, Harborview Med Ctr, Seattle, WA 98104 USA
[6] Virginia Tech, Caril Sch Med, Roanoke, VA USA
[7] Columbia Univ, Natl Ctr Disaster Preparedness, New York, NY USA
[8] British Columbia Childrens Hosp, Dept Pediat, Vancouver, BC, Canada
[9] British Columbia Childrens Hosp, Dept Emergency Med, Vancouver, BC, Canada
来源：
PEDIATRIC CRITICAL CARE MEDICINE | 2015年 / 16卷 / 02期
关键词：
adolescent; child; critical care; Ebola hemorrhagic fever; Ebola virus; Ebola virus disease; infant; sepsis; HEMORRHAGIC-FEVER; NONHUMAN-PRIMATES; RESPONSES; KIKWIT; CONGO; TRANSMISSION; PROTECTION; OUTBREAK;
D O I：
10.1097/PCC.0000000000000358
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Objectives: To provide clinicians with practical considerations for care of children with Ebola virus disease in resource-rich settings. Data Sources: Review of the published medical literature, World Health Organization and government documents, and expert opinion. Data Synthesis: There are limited data regarding Ebola virus disease in children; however, reported case-fatality proportions in children are high. Ebola virus may affect immune regulation and endothelial function differently in children than adults. Considerations for care of children with Ebola virus disease are presented. Conclusions: Ebola virus disease is a severe multisystem disease with high mortality in children and adults. Hospitals and clinicians must prepare to provide care for patients with Ebola virus disease before such patients present for care, with particular attention to rigorous infection control to limit secondary cases. Although there is no proven specific treatment for Ebola virus disease, meticulous supportive care offers patients the best chance of survival.
引用
收藏
页码：97 / 103
页数：7
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