Controlled Synthesis of Linear α-Cyclodextrin Oligomers Using Copper-Catalyzed Huisgen 1,3-Dipolar Cycloaddition

被引：28

作者：

Rawal, Girish K. ^{[1
]}

Zhang, Ping ^{[1
]}

Ling, Chang-Chun ^{[1
]}

机构：

[1] Univ Calgary, Alberta Ingenu Ctr Carbohydrate Sci, Dept Chem, Calgary, AB T2N 1N4, Canada

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 13期

关键词：

BETA-CYCLODEXTRIN; MOLECULAR RECOGNITION; CLICK CHEMISTRY; STRONG BINDING; DIMERS; INCLUSION; TRIMERS; ALKYNES; AZIDES;

D O I：

10.1021/ol101119p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The design and efficient synthesis of a novel class of linear oligomers based on cyclodextrins are described. These supramolecules have relatively rigid structures with well-defined topology and sizes, which could provide them with the ability to be used as scaffolds to present bioactive molecules to their receptors as well as host molecules.

引用

页码：3096 / 3099

页数：4

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