Sonogashira reaction on pyridinium N-heteroarylaminides

被引：9
作者：
Cordoba, Marta [1 ]
Luisa Izquierdo, M. [1 ]
Alvarez-Builla, Julio [1 ]
机构：
[1] Univ Alcala, Dept Quim Organ, Madrid 28871, Spain
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 15期
关键词：
Pyridinium N-aminides; Sonogashira; Microwaves; DABCO; CROSS-COUPLING REACTIONS; CATALYZED SUZUKI-MIYAURA; C BOND FORMATION; REGIOSELECTIVE SYNTHESIS; TERMINAL ALKYNES; ROOM-TEMPERATURE; ARYL BROMIDES; WATER; COMPLEX; DABCO;
D O I：
10.1016/j.tetlet.2011.01.121
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reactivity of N-(5-iodopyridin-2-yl)aminide in a copper-free Sonogashira cross-coupling process is reported. The reaction proceeds on using PdCl2(PPh3)(2) and DABCO as the base under microwave irradiation in acetonitrile or water as solvents. The process can also be carried out by traditional heating in acetonitrile on using Pd(AcO)(2)/DABCO with Cs2CO3. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1738 / 1741
页数：4
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