One-pot synthesis of 1,2,4-oxadiazoles mediated by microwave irradiation under solvent-free condition

被引：37

作者：

Kaboudin, B ^{[1
]}

Navaee, K ^{[1
]}

机构：

[1] IASBS, Dept Chem, Gava Zang 45195159, Zanjan, Iran

来源：

HETEROCYCLES | 2003年 / 60卷 / 10期

关键词：

D O I：

10.3987/COM-03-9769

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Microwave-assisted synthesis of 1,2,4-oxadiazoles of amidoximes under solvent free conditions was found to be an efficient method for one-pot synthesis of 1,2,4-oxadiazole derivatives from amidoximes and acyl chlorides. This method is an easy, rapid, and high-yielding reaction for the synthesis of 1,2,4-oxadiazoles.

引用

收藏

页码：2287 / 2292

页数：6

相关论文

共 28 条

[1] Oxadiazoles as bioisosteric transformations of carboxylic functionalities .2. [J].

Andersen, KE ;

Lundt, BF ;

Jorgensen, AS ;

Braestrup, C .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1996, 31 (05) :417-425

[2] Investigation of bioisosters of the growth hormone secretagogue L-692,429. [J].

Ankersen, M ;

Peschke, B ;

Hansen, BS ;

Hansen, TK .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1997, 7 (10) :1293-1298

[3] A simple and new method for the synthesis of 1,5-benzodiazepine derivatives on a solid surface [J].

Balakrishna, MS ;

Kaboudin, B .

TETRAHEDRON LETTERS, 2001, 42 (06) :1127-1129

[4]

BELL CL, 1961, J ORG CHEM, V26, P155

[5] MICROWAVE-ASSISTED ORGANIC-REACTIONS [J].

CADDICK, S .

TETRAHEDRON, 1995, 51 (38) :10403-10432

[6] 3-ARYL-2-(3'-SUBSTITUTED-1',2',4'-OXADIAZOL-5'-YL)TROPANE ANALOGS OF COCAINE - AFFINITIES AT THE COCAINE BINDING-SITE AT THE DOPAMINE, SEROTONIN, AND NOREPINEPHRINE TRANSPORTERS [J].

CARROLL, FI ;

GRAY, JL ;

ABRAHAM, P ;

KUZEMKO, MA ;

LEWIN, AH ;

BOJA, JW ;

KUHAR, MJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (20) :2886-2890

[7] IMPROVED FISCHER INDOLE REACTION FOR THE PREPARATION OF N,N-DIMETHYLTRYPTAMINES - SYNTHESIS OF L-695,894, A POTENT 5-HT1D RECEPTOR AGONIST [J].

CHEN, CY ;

SENANAYAKE, CH ;

BILL, TJ ;

LARSEN, RD ;

VERHOEVEN, TR ;

REIDER, PJ .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (13) :3738-3741

[8] A SIMPLIFIED PROCEDURE FOR PREPARING 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLES BY REACTION OF AMIDOXIMES WITH ACYL CHLORIDES IN PYRIDINE SOLUTION [J].

CHIOU, S ;

SHINE, HJ .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, 26 (01) :125-128

[9] 1,2,4-OXADIAZOLES [J].

CLAPP, LB .

ADVANCES IN HETEROCYCLIC CHEMISTRY, 1976, 20 :65-116

[10] OXADIAZOLES AS ESTER BIOISOSTERIC REPLACEMENTS IN COMPOUNDS RELATED TO DISOXARIL - ANTIRHINOVIRUS ACTIVITY [J].

DIANA, GD ;

VOLKOTS, DL ;

NITZ, TJ ;

BAILEY, TR ;

LONG, MA ;

VESCIO, N ;

ALDOUS, S ;

PEVEAR, DC ;

DUTKO, FJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (15) :2421-2436