Case Report: SARS-CoV-2 Infection-Are We Redeemed? A Report of Candida Spondylodiscitis as a Late Complication

被引:4
作者
Moreno-Gomez, Luis Miguel [1 ]
Esteban-Sinovas, Olga [1 ]
Garcia-Perez, Daniel [1 ]
Garcia-Posadas, Guillermo [1 ]
Delgado-Fernandez, Juan [1 ]
Paredes, Igor [1 ]
机构
[1] Univ Hosp 12 de Octubre, Dept Neurosurg, Madrid, Spain
关键词
COVID-19; candida; spondylodiscitis; corpectomy; antifungal therapy; VERTEBRAL OSTEOMYELITIS; POSTERIOR STABILIZATION; FUNGAL-INFECTIONS; ALBICANS;
D O I
10.3389/fmed.2021.751101
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: We describe a case of candida spondylodiscitis secondary to coronavirus disease (COVID-19).Case report: A 47-year-old man diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) required prolonged admission to the intensive care unit (ICU). Four months later, he was diagnosed with thoracic candida spondylodiscitis. Medical management was insufficient, so he eventually underwent surgery.Discussions: Fungal infections seem to be more likely in patients with COVID-19, but it is unknown whether they are directly attributed to COVID-19 or other surrounding factors. Regardless of the answer, the diagnosis is complicated, and the mortality rate is high.Lessons: COVID-19 is posing a challenge to the society, and new and unexpected diseases that had once disappeared have risen again. It is our duty to suspect them and to treat them in the most effective way possible.
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页数:6
相关论文
共 33 条
[1]   COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions? [J].
Arastehfar, Amir ;
Carvalho, Agostinho ;
Nguyen, M. Hong ;
Hedayati, Mohammad Taghi ;
Netea, Mihai G. ;
Perlin, David S. ;
Hoenigl, Martin .
JOURNAL OF FUNGI, 2020, 6 (04) :1-13
[2]   Bacterial and fungal superinfections in critically ill patients with COVID-19 [J].
Bassetti, Matteo ;
Kollef, Marin H. ;
Timsit, Jean-Francois .
INTENSIVE CARE MEDICINE, 2020, 46 (11) :2071-2074
[3]   Immunology of COVID-19 [J].
Brussow, Harald .
ENVIRONMENTAL MICROBIOLOGY, 2020, 22 (12) :4895-4908
[4]   Candida albicans lumbar spondylodiscitis in an intravenous drug user: A case report [J].
Chen C.-H. ;
Chen W.L. ;
Yen H.-C. .
BMC Research Notes, 6 (1)
[5]   Primary reconstruction for spinal infections [J].
Dietze, DD ;
Fessler, RG ;
Jacob, RP .
JOURNAL OF NEUROSURGERY, 1997, 86 (06) :981-989
[6]   Bone regeneration: current concepts and future directions [J].
Dimitriou, Rozalia ;
Jones, Elena ;
McGonagle, Dennis ;
Giannoudis, Peter V. .
BMC MEDICINE, 2011, 9
[7]   Fungal infections of the spine - Report of eleven patients with long-term follow-up [J].
Frazier, DD ;
Campbell, DR ;
Garvey, TA ;
Wiesel, S ;
Bohlman, HH ;
Eismont, FJ .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2001, 83A (04) :560-565
[8]   Invasive fungal diseases during COVID-19: We should be prepared [J].
Gangneux, J. -P. ;
Bougnoux, M. -E. ;
Dannaoui, E. ;
Cornet, M. ;
Zahar, J. R. .
JOURNAL DE MYCOLOGIE MEDICALE, 2020, 30 (02)
[9]   Better treatment of vertebral osteomyelitis using posterior stabilization and titanium mesh cages [J].
Hee, HT ;
Majd, ME ;
Holt, RT ;
Pienkowski, D ;
Rechtine, GR .
JOURNAL OF SPINAL DISORDERS & TECHNIQUES, 2002, 15 (02) :149-156
[10]   Spondylodiskitis due to Candida albicans: Report of two patients who were successfully treated with fluconazole and review of the literature [J].
Hennequin, C ;
Bouree, P ;
Hiesse, C ;
Dupont, B ;
Charpentier, B .
CLINICAL INFECTIOUS DISEASES, 1996, 23 (01) :176-178