Heterogeneity of Atlantic salmon troponin-I

被引：11

作者：

Jackman, DM

Pham, T

Noel, JJ

Waddleton, DM

Dhoot, GK

Heeley, DH ^{[1
]}

机构：

[1] Mem Univ Newfoundland, Dept Biochem, St Johns, NF A1B 3X9, Canada

[2] Univ London Royal Coll Vet Surg, Dept Basic Sci, London NW1 0TU, England

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY | 1998年 / 1387卷 / 1-2期

基金：

英国医学研究理事会;

关键词：

troponin-I; isoform; sequence analysis; (Atlantic salmon);

D O I：

10.1016/S0167-4838(98)00165-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three non-identical, full length troponin-I (Tn-I) clones were isolated from an Atlantic salmon myotomal (trunk) muscle cDNA library. The primary structures, which are predicted to range from 172 to 180 amino acids in length, exhibit similar percent identity scores when compared with fast, slow and cardiac specific Tn-Is from higher vertebrates. When the sequence data are considered along with the results of Western blotting it is evident that Tn-I is more heterogeneous in Atlantic salmon than has been previously shown in higher vertebrates. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：478 / 484

页数：7

共 34 条

[1]

CRESTFIELD AM, 1963, J BIOL CHEM, V238, P622

[2] DISTRIBUTION OF POLYMORPHIC FORMS OF TROPONIN COMPONENTS AND TROPOMYOSIN IN SKELETAL-MUSCLE [J].