Raising the Bar for Therapeutic Trials in Advanced Prostate Cancer

被引:2
作者
Alumkal, Joshi J. [1 ]
Beer, Tomasz M. [1 ]
机构
[1] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
关键词
DOCETAXEL PLUS PREDNISONE; PHASE-III TRIAL; DOUBLE-BLIND; CLINICAL-TRIALS; PLACEBO; MEN; CABOZANTINIB; MITOXANTRONE; COMBINATION;
D O I
10.1200/JCO.2016.68.0439
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:2958 / +
页数:5
相关论文
共 25 条
[1]   Why Do Phase III Clinical Trials in Oncology Fail so Often? [J].
Amiri-Kordestani, Laleh ;
Fojo, Tito .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2012, 104 (08) :568-569
[2]  
[Anonymous], P GEN CANC S
[3]   Androgen Receptor Splice Variant 7 and Efficacy of Taxane Chemotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer [J].
Antonarakis, Emmanuel S. ;
Lu, Changxue ;
Luber, Brandon ;
Wang, Hao ;
Chen, Yan ;
Nakazawa, Mary ;
Nadal, Rosa ;
Paller, Channing J. ;
Denmeade, Samuel R. ;
Carducci, Michael A. ;
Eisenberger, Mario A. ;
Luo, Jun .
JAMA ONCOLOGY, 2015, 1 (05) :582-591
[4]   AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer [J].
Antonarakis, Emmanuel S. ;
Lu, Changxue ;
Wang, Hao ;
Luber, Brandon ;
Nakazawa, Mary ;
Roeser, Jeffrey C. ;
Chen, Yan ;
Mohammad, Tabrez A. ;
Chen, Yidong ;
Fedor, Helen L. ;
Lotan, Tamara L. ;
Zheng, Qizhi ;
De Marzo, Angelo M. ;
Isaacs, John T. ;
Isaacs, William B. ;
Nadal, Rosa ;
Paller, Channing J. ;
Denmeade, Samuel R. ;
Carducci, Michael A. ;
Eisenberger, Mario A. ;
Luo, Jun .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (11) :1028-1038
[5]   Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): a randomised, double-blind phase 3 trial [J].
Araujo, John C. ;
Trudel, Geralyn C. ;
Saad, Fred ;
Armstrong, Andrew J. ;
Yu, Evan Y. ;
Bellmunt, Joaquim ;
Wilding, George ;
McCaffrey, John ;
Serrano, Sergio V. ;
Matveev, Vsevolod B. ;
Efstathiou, Eleni ;
Oudard, Stephane ;
Morris, Michael J. ;
Sizer, Bruce ;
Goebell, Peter J. ;
Heidenreich, Axel ;
de Bono, Johann S. ;
Begbie, Stephen ;
Hong, Jun H. ;
Richardet, Eduardo ;
Gallardo, Enrique ;
Paliwal, Prashni ;
Durham, Susan ;
Cheng, Shinta ;
Logothetis, Christopher J. .
LANCET ONCOLOGY, 2013, 14 (13) :1307-1316
[6]  
Chi KN, 2015, J CLIN ONCOL S, V33
[7]   Castration-Resistant Prostate Cancer: AUA Guideline Amendment [J].
Cookson, Michael S. ;
Lowrance, William T. ;
Murad, Mohammad H. ;
Kibel, Adam S. .
JOURNAL OF UROLOGY, 2015, 193 (02) :491-499
[8]   American Society of Clinical Oncology Perspective: Raising the Bar for Clinical Trials by Defining Clinically Meaningful Outcomes [J].
Ellis, Lee M. ;
Bernstein, David S. ;
Voest, Emile E. ;
Berlin, Jordan D. ;
Sargent, Daniel ;
Cortazar, Patricia ;
Garrett-Mayer, Elizabeth ;
Herbst, Roy S. ;
Lilenbaum, Rogerio C. ;
Sima, Camelia ;
Venook, Alan P. ;
Gonen, Mithat ;
Schilsky, Richard L. ;
Meropol, Neal J. ;
Schnipper, Lowell E. .
JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (12) :1277-+
[9]   Phase III, Randomized, Placebo-Controlled Study of Docetaxel in Combination With Zibotentan in Patients With Metastatic Castration-Resistant Prostate Cancer [J].
Fizazi, Karim S. ;
Higano, Celestia S. ;
Nelson, Joel B. ;
Gleave, Martin ;
Miller, Kurt ;
Morris, Thomas ;
Nathan, Faith E. ;
McIntosh, Stuart ;
Pemberton, Kristine ;
Moul, Judd W. .
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (14) :1740-+
[10]   Assumptions of Expected Benefits in Randomized Phase III Trials Evaluating Systemic Treatments for Cancer [J].
Gan, Hui K. ;
You, Benoit ;
Pond, Gregory R. ;
Chen, Eric X. .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2012, 104 (08) :590-598